Sr. Research Associate, Single Cell Assay Productization (Contract) (P-4977)
About The Position
We are seeking a Senior Research Associate to join the Assay Productization team to support the development and commercial launch of new Single Cell Genomic products on a six months contract basis, with the potential to extend. Assay Productization acts as the interface between R&D and Production. The team is involved in all stages of product development from concept to post-launch activities. This is a unique cross-disciplinary position that will work closely with a variety of groups including Molecular Biology, Chemistry, Microfluidics, QC, and Manufacturing, to develop and validate novel reagents for the rapid expansion of 10x product lines. Candidates must have a broad working knowledge of molecular biology and be able to apply that knowledge creatively and independently in a fast-paced work environment. Research experience with DNA oligos, antibody assays, RNA assays, and next generation sequencing (NGS) is desired. Experience in new product introduction and manufacturing operations is a big plus.This role requires a candidate who can be relied upon to produce consistent, high-quality data without needing daily tasks assigned.
Requirements
- BS or MS in molecular biology, biochemistry, genetics, analytical chemistry, or related fields.
- 3+ years (BS) or 2+ years (MS) of experience in reagent or assay development, preferably within the Biotech industry.
- Deep understanding of molecular biology and hands-on experience with NGS library generation and data evaluation.
- Mastery of analytical techniques including qPCR, nucleic acid isolation, and use of Bioanalyzers or real-time PCR instruments.
- Ability to perform complex multi-step experiments with detailed and diligent attention to planning, organization, hands-on technique, and record keeping.
- Experience troubleshooting molecular biology-based assays.
- Strong collaboration and communication skills.
- Desire to work in a flexible and fast-paced startup environment.
Nice To Haves
- Previous work with a variety of NGS sample preparation workflows and analysis.
- Strong preference for single cell and/or RNA-Seq workflows.
- Past work in a process or product development role, especially technology transfer to manufacturing and/or QC groups.
- Experience working with new and untested reagents.
- Experience creating and optimizing novel assays.
Responsibilities
- Create NGS libraries from single cells, tissues, or isolated DNA/RNA using 10x instruments and consumables.
- Preparation, formulation, and testing of newly designed 10x reagents either from SOPs or R&D protocols.
- Assist with reagent guard banding and stability studies.
- Assist with new QC method development and implementation to assess reagent quality through a variety of analytical and functional tests.
- Perform troubleshooting analysis of failed experiments and reagent issues as they arise in the product line.
- Facilitate successful handoffs from R&D to Operations by training QC and Production staff on new workflows or methods.
- Present your own work to internal stakeholders, providing clear explanations of methodology and data interpretation.
Benefits
- comprehensive health benefit program
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
