Senior Project Manager

JLL•South San Francisco, CA

1d•$110,000 - $150,000•Onsite

About The Position

JLL empowers you to shape a brighter way. Our people at JLL are shaping the future of real estate for a better world by combining world class services, advisory and technology for our clients. We are committed to hiring the best, most talented people and empowering them to thrive, grow meaningful careers and to find a place where they belong. Whether you’ve got deep experience in commercial real estate, skilled trades or technology, or you’re looking to apply your relevant experience to a new industry, join our team as we help shape a brighter way forward. Position Overview Senior Project Manager Responsible for the end-to-end delivery of life sciences capital projects, including GxP facility renovations (minor and major), new laboratory/manufacturing builds, and critical utility infrastructure upgrades. This role ensures all projects maintain a "state of control" and meet stringent regulatory requirements.

Requirements

Bachelor’s degree in Engineering (Mechanical, Chemical, or Civil), Construction Management, Architecture, or a related scientific field.
PMP (Project Management Professional) certification.
7–10 years of project management experience in complex technical construction.
5+ years of specific experience in Life Sciences, Biotech, or Pharmaceutical environments.
Proven track record managing GMP facility capital projects ($1M–$25M+), including cleanroom build-outs (ISO 5–8), laboratory renovations, and critical infrastructure (validated HVAC, WFI/RO high-purity water, and EMS).
Expertise in overseeing the technical integration of manufacturing skids, analytical instrumentation, and specialized containment areas (e.g., BSL-2/3).
Deep understanding of FDA (21 CFR Part 211) and EMA regulatory requirements.
Experience interfacing with local authorities, including zoning and specialized fire/safety code officials for hazardous material storage.
Mastery of the V-Model approach, including IQ/OQ/PQ protocols and Turnover Packages (TOP).
Direct experience managing Change Controls, Deviations, and CAPAs within a regulated project lifecycle.
Proficiency in MS Project or Primavera P6.
Expertise in budget forecasting and mitigating "scope creep" in highly regulated environments.
Ability to perform FMEA (Failure Mode and Effects Analysis) to protect product integrity during construction.
In-depth knowledge of ISO 14644 standards and Grade A–D operational requirements.
Understanding of unidirectional flow for personnel, material, and waste to prevent cross-contamination.
Proficiency in BIM/VDC platforms (Autodesk Construction Cloud, Procore) and document control for audit-ready project files.
Ability to lead teams of MEP engineers, Validation specialists, QA/QC officers, and Architects of Record.
Ability to present project risks and financial health to C-suite stakeholders and Steering Committees.
Skill in negotiating with specialized sub-contractors and vendors (e.g., orbital welders, cleanroom panel installers).
Ability to assess if a construction delay or field change impacts the validated state of the facility.
Applying "Lean Construction" or specialized methodologies to minimize downtime during facility shutdowns.
Candidates must be authorized to work in the United States without sponsorship.

Nice To Haves

ISPE (International Society for Pharmaceutical Engineering) membership or LEED AP certification.
Experience with Brownfield projects (renovating active GMP facilities without interrupting production).
Familiarity with Digital Plant initiatives (Smart Buildings, IoT sensors for monitoring, and Lab Automation).

Responsibilities

Responsible for the end-to-end delivery of life sciences capital projects, including GxP facility renovations (minor and major), new laboratory/manufacturing builds, and critical utility infrastructure upgrades.
Ensure all projects maintain a "state of control" and meet stringent regulatory requirements.
Lead teams of MEP engineers, Validation specialists, QA/QC officers, and Architects of Record.
Present project risks and financial health to C-suite stakeholders and Steering Committees.
Negotiate with specialized sub-contractors and vendors (e.g., orbital welders, cleanroom panel installers).
Assess if a construction delay or field change impacts the validated state of the facility.
Apply "Lean Construction" or specialized methodologies to minimize downtime during facility shutdowns.
Achieve 95%+ on-time delivery (aligned with manufacturing production schedules).
Adhere 100% within approved budget, including management of contingency.
Achieve zero "Major" findings during Quality/Regulatory audits of project files.
Maintain a safety record of zero lost-time incidents; 100% compliance with site-specific EHS protocols.
Ensure successful transition from "Mechanical Completion" to "Operational Readiness" with minimal punch-list items.