Senior Manager, Sales Operations

Day One BiopharmaceuticalsBrisbane, CA
8h$170,000 - $180,000Remote

About The Position

At Day One, we are focused on advancing first- or best-in-class medicines for childhood and adult diseases with equal intensity. We were founded to address the lack of new therapies resulting from the traditional drug development model, that has left children with cancer and their families waiting too long for new, life-changing treatments. Our aim is to accelerate better, targeted treatments so patients of any age can look forward from ‘day one’ to the future they’ve envisioned. POSITION SUMMARY: The Senior Manager, Sales Operations will play a critical role in supporting the ongoing commercial success of our therapy for pediatric low-grade glioma. This individual will serve as a key partner to the field organization, driving performance insights, enabling data-driven decision-making, and optimizing sales execution in a highly specialized rare-disease oncology environment. Reporting to the Senior Director, Commercial Analytics, the ideal candidate brings deep experience in sales operations, strong analytical capabilities, fluency working with commercial data sources, and the ability to effectively partner with field sales leadership. This role is highly cross-functional and requires strategic thinking, technical proficiency, and exceptional communication skills. This position has the potential to be fully remote although SF Bay area with ability to be in home office 2 days/week a plus. Occasional travel will be required for in person meetings.

Requirements

  • Bachelor’s degree in Business, Analytics, Life Sciences, or related field; advanced degree a plus.
  • 5–7+ years of experience in pharmaceutical/biotech Sales Operations and/or Commercial Analytics.
  • Strong analytical and quantitative skills with proficiency in Excel, BI tools (DOMO, Tableau, Power BI, Qlik, etc.), and CRM systems (Veeva preferred).
  • Experience supporting field sales teams and collaborating directly with field leadership.
  • Demonstrated ability to synthesize complex data into clear insights and recommendations.
  • Solid understanding of U.S. pharmaceutical data sets (e.g., claims, specialty pharmacy, HUB, distribution).
  • Strong project management, communication, and stakeholder engagement skills.

Nice To Haves

  • Experience in rare disease, oncology, or small-volume/high-complexity product environments.
  • Comfortable working in a fast-paced, build-as-you-go environment associated with emerging biotech.
  • Familiarity with patient-finding methodologies and advanced targeting analytics.
  • Prior experience managing or administering incentive compensation programs.

Responsibilities

  • Field Analytics & Reporting: Develop, automate, and maintain dashboards and reporting Applications for field sales leadership and field teams. Provide actionable insights on field performance, geographic trends, physician and account level analytics, and patient enrollment dynamics. Provide regular leadership updates in sales performance and IC rankings Partner with field advisory teams to evaluate and enhance reporting deliverables.
  • Patient-Finding & Data Enablement Partner with Commercial Operations and Sales Leadership to support patient identification strategies using claims data, EMR data, specialty pharmacy data, and other rare-disease data assets. Create territory-level patient opportunity assessments and support field deployment of targeting tools.
  • Incentive Compensation (IC) Design, manage, and administer incentive compensation plans and contests for field teams, ensuring fairness, motivation, and alignment with strategic objectives. Partner with Field Advisory teams to develop and create advocacy with IC plans. Model IC scenarios, process quarterly IC validation, manage payouts, and ensure compliance with policies and legal guidelines. Partner closely with IC Steering Committee to ensure alignment on plan performance and communication.
  • Customer-Level Insights Generate insights at the healthcare provider (HCP), institution, and network level to guide targeting, segmentation, pull-through and account planning. Translate complex data trends into actionable recommendations for field leadership. Monitor customer behavior, adoption patterns, and market dynamics.
  • CRM Ownership & Optimization Serve as commercial business owner for the CRM (e.g., Veeva), ensuring field usability, data integrity, and continuous enhancement. Translate field requirements into CRM configurations, workflows, and reporting improvements. Train, support, and develop CRM best practices across the field team.
  • Cross-Functional Leadership Collaborate closely with Sales, Marketing, Market Access, Data Management and IT teams to align operational processes and data strategy. Serve as a thought partner to sales leadership on execution strategy, performance diagnostics, and field enablement. Support launch readiness activities, process buildout, and ongoing commercial evolution.
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