Senior Manager – Partner, Global Health Economics

Takeda•Boston, MA

1d•Hybrid

About The Position

OBJECTIVES/PURPOSE Contribute to the development and execution of health economics (HE) strategies and plans for Takeda oncology medicines. Drive hands-on economic assessments for Takeda oncology medicines at all stages of development, using HE models and materials including systematic literature reviews (SLRs), indirect treatment comparisons (ITCs), statistical analyses of trial and real-world data and other methods as appropriate Collaborate with cross-functional counterparts to inform clinical development plans, evidence generation activities support, global market access plans, and pricing decisions Lead development of Global HE materials and provide support for country adaptations to regional and local operating company (LOC) patient value & access (PVA) and HE leads. Oversee country roll-out and training on global HE materials and support country response to payer inquiries Propose and co-lead robust publication plans for portfolio medicines through life cycle management, as well as above-brand initiatives and activities aligned with Global Oncology HE and Global Oncology Pricing, Value & Access (PVA) priorities

Requirements

Doctorate with 1+ years of experience, Master's with 2+ years of experience or Bachelor's with 4+ years of experience in healthcare industry with direct experience in global product value proposition development (industry or consulting) and interaction with payers, HTA bodies, relevant policymakers and strong patient-centered focus
Good understanding of the global payer environment and of ex-US payer landscape including HTA trends and guidance (e.g., NICE, CADTH, PBAC), along with knowledge of US Medicare (Part D), ICER in the US and trends in Emerging Markets (e.g., China) – including reimbursement methodologies, pricing/reimbursement authorities’ decision-making process and current reimbursement issues
Knowledge and hands on experience in health economics, HTA tools, methods and filings, SLRs, ITCs, statistical analyses and economic modelling
Understanding of clinical and epidemiological information, innovative global pricing models, all phases of drug development methods of analysis of large databases (e.g., claims data, electronic health records) and the major areas of Outcomes Research (PROs, patients preferences)
Ability to work in a highly matrixed organization
Strong analytical capabilities and excellent communication skills (written and oral)
Demonstrated problem solving capability
Influencing skills with the ability to effective drive decision making
Ability to translate technical issues to non-technical experts
5 to 10% Domestic and/or International travel required

Nice To Haves

Previous experience in Oncology
A combination of Global and US HE-related experience with knowledge of HTA requirements AND experience in HTA submissions
Peer-reviewed publications and/or oral and poster presentations at scientific conferences

Responsibilities

HE and Value & Access Tools Develop early HE models and comparative efficacy/effectiveness analyses to contribute to target product profiles and clinical development plans by understanding and communicating relevant HE and related outcome measures needed to achieve market access, including testing efficacy and pricing hypotheses, prioritizing payer-relevant evidence generation, and planning for health technology appraisals (HTA; including the EU Joint Clinical Assessment [JCA]) accross markets
Lead the development of state of the art HE models and studies (e.g., SLRs, ITCs) with sufficient evidentiary support to withstand critique of HTA bodies and other key access decision makers
Lead training to Regions and LOCs on product value, new evidence and HE studies and models
Payer-related Evidence Generation Contribute to evidence generation planning to optimally demonstrate the product clinical, economic and humanistic value to payers, HTA bodies, and market access decision makers, and ensure payer and HE evidence needs are incorporated into Global, Regional and Local activities
Evaluate the anticipated outcome of key HTAs (including JCA) and the implications for value positioning and evidence requirements, and shape the product’s ongoing evidence generation plan in partnership with Global PVA, Global Evidence and Outcomes (GEO) and Global Medical Affairs Oncology (GMAO)
Make recommendations to cross-functional business partners about the need for additional data generation – clinical trial, real world evidence (RWE) such as registries and databases – based on evidentiary requirements of payers and HTA bodies
Ensure the integration of payer-relevant HE endpoints and evidence needs in the clinical development plans
Global Value Proposition and Market Access Establish a comprehensive understanding of the burden of disease(s), unmet need and appropriate comparator
Support Global PVA colleagues the development of the global value proposition to ensure a compelling value story for payers
Support the development, review, and updating of the product value platform, including but not limited to Value Story, Global Value Dossiers, Objection Handler, Global Pricing Guidance
Maintain awareness of the quickly evolving Global HTA (including JCA) and reimbursement landscape and the evidentiary needs of health care decision-makers to guide HE and market access strategies
Communication/Publication and Foster Superior Collaboration Communicate and translate HE messages effectively in manuscripts, posters and publications, and support the development of appropriate communication tools for clinicians and payers as needed
Foster productive collaboration and effectively manage several important partnerships and consultants to achieve impact and contribute to the company’s success. These interfaces include but are not limited to Regional and Local PVA leads, US Payer Marketing and Market Access, GEO, GMAO, Biostatistics, Global Emerging Markets (GEM; e.g., China), Project Leadership, Finance, Corporate Communications and Business Development
Ensure excellence in HE activities and being up to date on the latest and most innovative HE, HTA, and RWE methods

Benefits

U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others.
U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

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