Senior Associate Scientist, Pharmacology

Bristol Myers Squibb • San Diego, CA

49d • Onsite

About The Position

This laboratory-based role offers an exciting opportunity to advance novel radiopharmaceutical therapies from bench to bedside. The Senior Associate Scientist will participate in discovery and translational research by conducting in vivo experiments and managing vivarium duties, including experiment design, execution, tissue collection, and data analysis. The role also includes in vitro mechanistic studies and cross-functional collaboration with teams in translational research, medicinal chemistry, and other scientific disciplines. The successful candidate will receive mentorship from senior scientists and must adhere strictly to radiation safety protocols.

Requirements

• B.Sc. with 4-5+ years of experience or M.Sc. with 2-3+ years of experience in Biology, Pharmacology, Translational Research, Molecular Biology, or a related discipline.
• Prior hands-on experience in pre-clinical drug discovery programs (industrial or academic settings) is preferred.
• Prior experience working with radioactive materials is strongly preferred.
• Technical proficiency in rodent handling (immune-compromised and -competent mice), aseptic procedures, and lab animal research.
• Ability to perform IV compound administration and SC engraftment is mandatory.
• Hands-on experience with cell-based assays, molecular biology techniques (ELISA, western blot, qPCR, immunohistochemistry), and related protocols.
• Working knowledge of MS 365 and GraphPad Prism.
• Strong work ethic, self-motivation, adaptability, and organizational skills.
• Ability to work in a fast-paced, dynamic, and collaborative environment.
• Excellent written, oral communication, and presentation skills.

Nice To Haves

• Experience with in vivo imaging modalities is a plus.
• Familiarity with the drug development process and interdisciplinary teamwork.

Responsibilities

• Design and execute in vivo studies using CDX, PDX, and syngeneic mouse models to evaluate tumor growth kinetics, biodistribution, therapeutic efficacy, and durability of response across various treatment modalities, including radiopharmaceutical agents.
• Perform essential in vivo procedures: cell culture, tumor cell and PDX fragment implantation, sampling, dosing (IV, SC, IP, PO), tumor and body weight monitoring, and necropsy.
• Analyze and interpret experimental data independently; present findings at project team meetings, departmental reviews, and company-wide forums.
• Conduct in vitro experiments (e.g., cell viability, cytotoxicity, proliferation, apoptosis, DNA damage response, pathway interrogation) using molecular biology techniques.
• Work with radioactive materials in strict compliance with institutional and federal radiation safety protocols.
• Support laboratory operations, including inventory management, equipment maintenance, and ensure strict compliance with company policies, GLP, IACUC, and animal welfare guidelines, including accurate documentation in laboratory notebooks and electronic records.
• Collaborate effectively within the immediate team and cross-functionally to advance program objectives.
• Demonstrate initiative and technical expertise in troubleshooting experimental issues and ensuring accurate data analysis.
• May involve working outside standard business hours, including weekends, holidays, and early mornings, to support critical in vivo studies and project deadlines.

Benefits

• Medical, pharmacy, dental and vision care.
• Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP).
• Financial well-being resources and a 401(K).
• Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support.
• Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility.
• Parental, caregiver, bereavement, and military leave.
• Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources.
• Other perks like tuition reimbursement and a recognition program.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Industry: Chemical Manufacturing
• Number of Employees: 5,001-10,000 employees