Scientist I - In Vitro Pharmacology

UCBCambridge, MA
1dHybrid

About The Position

We are seeking to hire an exceptional Scientist - In Vitro Pharmacology to join the US In Vitro Pharmacology group based in Cambridge, MA and to contribute to drug discovery efforts with an emphasis on muscle biology. This is a lab-based function with the responsibility of designing, characterizing and deploying in vitro models and other cellular/biochemical assays to be utilized in early drug discovery for multiple therapeutic programs and target discovery efforts.This is a lab-based function with the responsibility of designing, characterizing and deploying in vitro models and other cellular/biochemical assays to be utilized in early drug discovery for multiple therapeutic programs and target discovery efforts.

Requirements

  • Either an MS with >4 years of industry experience OR a PhD with 0-2 years relevant experience
  • Skeletal muscle biology expertise
  • Experience and working knowledge of in vitro pharmacology, cell biology, molecular biology, and lab automation
  • Excellent communication skills with the proven ability to build collaborative relationships and work effectively as a member of a multidisciplinary team
  • Works under general direction and may consult management to obtain information to build consensus and project direction.
  • Has thorough knowledge and understanding of concepts and subject matter expertise

Nice To Haves

  • Experience with culturing a broad variety of mammalian cells; proficiency with maintenance and differentiation of iPSCs and primary cell lines
  • Experience training junior researchers
  • Experience with in vivo disease models and ex vivo pharmacology

Responsibilities

  • Assay Development: Design, characterize and validate bespoke assays to support muscle therapeutic programs.
  • Assay Execution: Conduct cell-based functional assays to characterize compounds or validate new targets.
  • Muscle Biology: Perform in vitro assays to enhance understanding of neuromuscular disease biology.
  • Team Collaboration: Collaborate with cross-functional teams to integrate translational biology insights into therapeutic programs or new target proposals.
  • Data Management: Document, analyze, and present data to internal teams.

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What This Job Offers

Job Type

Full-time

Career Level

Entry Level

Education Level

Ph.D. or professional degree

Number of Employees

5,001-10,000 employees

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