Senior Associate Scientist, In Vitro Pharmacology

Pfizer • Cambridge, MA

7d • Onsite

About The Position

At Pfizer, our purpose is to deliver breakthroughs that change patients’ lives. As a Senior Associate Scientist Biology, you will be at the forefront of our mission, contributing to the development of innovative therapies and vaccines that have the potential to transform patient care. Reporting to the Research & Development division, you will leverage advanced science and cutting-edge technologies to make a tangible impact on global health. Your work will be instrumental in ensuring drug safety and efficacy, supporting clinical trials, and accelerating the delivery of top-tier medicines to patients worldwide.

Requirements

• Bachelor’s degree in Immunology or Pharmacology with 3+ years experience performing in vitro based experiments in a Pharma/Biotech lab environment.
• Previous experience in generating and analyzing single and multicolor flow cytometry data.
• Experience with MSD & ELISA experimentation.
• Experience in plate-based experimentation and serial dilutions of large and small molecules.
• Strong understanding of fundamental in vitro pharmacology parameters and how to design and execute plate-based experiments to quantify them.
• Confidence in troubleshooting experimental/assay challenges.
• Good sterile techniques for culture and maintenance to primary and immortalized cell lines.
• Competent user of Excel, GraphPad Prism and PowerPoint for data analysis and presentation of results.

Nice To Haves

• Prior experience in working with both large and small molecule therapeutic modalities.
• Experience in drug discovery processes.
• Excellent organizational and time management skills.

Responsibilities

• Be responsible for the design, development and execution of in vitro experiments to generate decision making data for portfolio programs.
• Become an integral member of research project biology teams where you will be responsible for recommending options for in vitro experimentation, generation of high-quality in vitro pharmacology data and report results and conclusions at project team meetings.
• Design develop and execute in vitro experiments to assess the potency and efficacy of molecules.
• Utilize single and multicolor flow cytometry to assess affinity and potency of molecules.
• Perform single and multiplexed MSD/conventional ELISA experiments to quantify cellular cytokine release.
• Work with whole blood and perform isolation and differentiation of cell subsets.
• Independently perform data analysis and present results at project meetings.

Benefits

• In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary.
• We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments.
• Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level