Scientific Director, Metabolite Profiling Core Facility

MIT • Cambridge, MA

11d

About The Position

SCIENTIFIC DIRECTOR , Koch Institute (KI) for Integrative Cancer Research - Metabolite Profiling Core Facility , to support metabolism-based research projects in a variety of experimental models through the use of high-resolution, accurate-mass, liquid chromatography mass spectrometry. Responsibilities include overseeing and further developing the operation of a state-of-the-art facility consisting of targeted and untargeted metabolomics and lipidomics platforms using high-resolution, accurate-mass, liquid chromatography mass spectrometry (LC/MS); collaborating with and advising scientists at KI, MIT, Whitehead Institute, and external institutions on developing and applying LC/MS-based metabolomic/lipidomic experiments to advance the research; consulting on experimental design, analyzing and interpreting metabolomic/lipidomic data, and developing new LC/MS-based assays as projects dictate; participating in grant writing and manuscript preparation and on the acquisition of new equipment to expand and advance scientific applications; and performing other duties as assigned.

Requirements

• Ph.D. in biological/physical sciences or a related discipline
• a minimum of four years of research experience, preferably in a biological/biomedical setting
• comprehensive understanding of quantitative methods in mass spectrometry and metabolomics, including instrument operation, sample preparation, and data analysis
• experience with lipidomics or willingness/ability to learn
• strong communication, troubleshooting, and problem solving skills
• ability to collaborate with scientists to consult on experimental design, data analysis, and interpretation
• supervisory experience
• ability to work as part of a team

Nice To Haves

• Working knowledge of Orbitrap systems and accompanying software
• understanding of the use of stable isotopes in tracing experiments
• broad knowledge of high-resolution accurate-mass data analysis software

Responsibilities

• overseeing and further developing the operation of a state-of-the-art facility consisting of targeted and untargeted metabolomics and lipidomics platforms using high-resolution, accurate-mass, liquid chromatography mass spectrometry (LC/MS)
• collaborating with and advising scientists at KI, MIT, Whitehead Institute, and external institutions on developing and applying LC/MS-based metabolomic/lipidomic experiments to advance the research
• consulting on experimental design, analyzing and interpreting metabolomic/lipidomic data, and developing new LC/MS-based assays as projects dictate
• participating in grant writing and manuscript preparation and on the acquisition of new equipment to expand and advance scientific applications
• performing other duties as assigned

What This Job Offers

• Job Type: Full-time
• Career Level: Director
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees