Metabolite Isolation Intern

Neurocrine Biosciences
1d

About The Position

Neurocrine Biosciences, Inc. (NASDAQ: NBIX) is offering the opportunity to gain experience in isolating drug metabolites by UPLC/MS-Fraction collection in the world of biotechnology. Our intern program offers exposure to biosynthesis of metabolites using sub-cellular liver fractions, semi-preparative chromatography, HRMS (high resolution mass spectrometry), and possibly NMR (Nuclear Magnetic Spectroscopy). The Biotransformation team has a strong reputation in the industry for metabolite identification.

Requirements

  • Pursuing an undergraduate degree with an interest in biotechnology
  • Specific degree or field required: The ideal candidate would be in their 3rd or 4th year pursuing an undergraduate degree in chemistry, biology, biotechnology, or relevant pharmaceutical sciences.
  • Familiarity with biopharmaceutical technologies, physical and life sciences, product development, and regulatory approval processes is desirable
  • Good verbal and written communication skills
  • Ability to think creatively and be a team player
  • Offer flexibility with a willingness to work on multiple projects simultaneously
  • Bring to the Company a skill set complementary to its technology and development therapeutics
  • Interest in attending various program events, including social gatherings, career development workshops, and more
  • Ability to commit to a 10-week, full-time summer program
  • Part-time. A significant amount of time will be spent lab based but remote access of instrumentation, data analysis, and presentation of results from office space are also a part of the role.

Nice To Haves

  • Prior experience in the pharmaceutical or biotechnology industry would be an asset but is not required

Responsibilities

  • Working with sub-cellular fractions (liver microsomes, and S9) to generate metabolites.
  • Working with semi-preparative UPLC-Fraction collector to isolate metabolites from parent compound.
  • Analysis of individual fractions by UPLC/HRMS to confirm fraction isolation of metabolite.
  • Interacting with drug metabolism areas within the company
  • Collaborating with a mentor team of cross-functional team members as well as the other interns in the class
  • Completing a special project and presenting the recommendations to senior management upon completion
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