Research Technician

Mass General Brigham•Boston, MA

19h•$20 - $29•Onsite

About The Position

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Bioanalytical research technician (RT) position available at the A. A. Martinos Center for Biomedical Imaging at Massachusetts General Hospital in Charlestown to support the development of molecular imaging probes. The RT works as part of a team to perform research studies. The RT collects and analyzes study data as well as documents, compiles and maintains research data. Job Summary Summary: Responsible for maintaining laboratory equipment, organizing and preparing samples, conducting experiments, and recording and analyzing data. Candidates who are in the process of completing their bachelor's degree have a grace period of six months from their hire date (up to 1 year if starting per diem) to provide degree equivalency verification. Essential Functions: -Perform laboratory experiments following established protocols and procedures. -Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines. -Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed. -Record experimental data accurately and maintain organized records of procedures, protocols, and results. -Compile and analyze data using appropriate statistical and analytical methods. -Assist in data interpretation and presentation, contributing to research findings and reports. Qualifications Education Bachelor's Degree Related Field of Study required PRINCIPAL DUTIES AND RESPONSIBILITIES: We are seeking a full-time Research Technician to take on several job responsibilities. We will train all employees. The major responsibilities we are looking for a Research Technician to take on are: High performance liquid chromatography (HPLC) analysis of chemical and biological samples using absorbance, fluorescence, or mass spectrometry detection Candidate will be trained but HPLC experience is a plus. Candidate must: Prepare samples for analyses from biological matrices Prepare standards and calibrate instruments Run analyses and analyze data Generate data summaries to report to senior scientists Maintain and troubleshoot instruments Inductively coupled plasma mass spectrometry (ICP-MS) of samples for elemental analysis. Candidate must: Prepare samples for analyses from biological matrices Prepare standards and calibrate instruments Run analyses and analyze data Generate data summaries to report to senior scientists Maintain and troubleshoot instruments Elemental imaging of tissue sections by laser ablation (LA)-ICP-MS. Candidate must: Cut tissue sections for analyses Prepare standards and calibrate instruments Run analyses and analyze data Generate data summaries to report to senior scientists Maintain and troubleshoot instruments Biochemical assays and histology General wet lab knowledge is required for this project A variety of assays using standard protocols are performed in the lab. These involve: Protein preparation, purification, quantification using standard techniques like FPLC, BCA assay, Western blot, SDS-PAGE UV-Vis, Fluorescence, NMR, and HPLC readouts Data analysis using Excel or GraphPad Prism Perform routine histological staining of tissue sections following standard protocols. Reporting data summaries to senior scientists Inorganic syntheses Occasional preparation of metal complexes used as molecular imaging probes Formulation and analysis of the probe solutions

Requirements

Bachelor's Degree Related Field of Study required
General wet lab knowledge is required for this project
The successful candidate will be expected to work independently and willing to master new techniques.

Nice To Haves

HPLC experience is a plus.

Responsibilities

High performance liquid chromatography (HPLC) analysis of chemical and biological samples using absorbance, fluorescence, or mass spectrometry detection
Prepare samples for analyses from biological matrices
Prepare standards and calibrate instruments
Run analyses and analyze data
Generate data summaries to report to senior scientists
Maintain and troubleshoot instruments
Inductively coupled plasma mass spectrometry (ICP-MS) of samples for elemental analysis.
Prepare samples for analyses from biological matrices
Prepare standards and calibrate instruments
Run analyses and analyze data
Generate data summaries to report to senior scientists
Maintain and troubleshoot instruments
Elemental imaging of tissue sections by laser ablation (LA)-ICP-MS.
Cut tissue sections for analyses
Prepare standards and calibrate instruments
Run analyses and analyze data
Generate data summaries to report to senior scientists
Maintain and troubleshoot instruments
Biochemical assays and histology
Protein preparation, purification, quantification using standard techniques like FPLC, BCA assay, Western blot, SDS-PAGE UV-Vis, Fluorescence, NMR, and HPLC readouts
Data analysis using Excel or GraphPad Prism
Perform routine histological staining of tissue sections following standard protocols.
Reporting data summaries to senior scientists
Inorganic syntheses
Occasional preparation of metal complexes used as molecular imaging probes
Formulation and analysis of the probe solutions
Responsibilities include operation and routine maintenance of laboratory instruments (ICP, HPLC, LC-MS), execution and interpretation of bioanalytical assays, ordering and maintaining inventory of laboratory supplies.