The Ackerman lab (Department of Pathology and Immunology, Center for Brain Immunology and Glia) studies molecular mechanisms underlying neural plasticity and neurodegeneration using zebrafish and fruit fly model systems. We use traditional and cutting-edge genetic strategies to identify new mechanisms used by glial cells (astrocytes, oligodendrocytes, and microglia) to sculpt brain wiring, and to understand how this contributes to a variety of neurological diseases. With the support of a new R01 from the NINDS, the Ackerman lab has recently expanded its scope to explore how glial cells metabolically support neurons through dynamic transport and transfer of their mitochondria. Candidates should have educational or training experience in the biological sciences, and an enthusiasm for new challenges and opportunities. Assists with the technical aspects of studies and experiments, including documentation and preparation of materials. Additional Details about the Lab: • Our laboratory uses animal models (zebrafish and Drosophila) to understand how the brain develops and functions. • The goal of the NIH-supported research is to explore how neuronal activity influences mitochondrial dynamics in neurons and associated glia in Drosophila. • We utilize reverse genetics, optogenetics, CRISPR/Cas9 mutagenesis, transgenesis, confocal microscopy, and behavioral readouts to interrogate the nervous system.
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Job Type
Full-time
Career Level
Entry Level
Number of Employees
5,001-10,000 employees