Research Manager D, Rodent Metabolic Phenotyping Core

University of Pennsylvania Perelman School of Medicine•Philadelphia, PA

1d•Onsite

About The Position

The Research Manager D will serve as the daily manager for all activities within the Institute for Diabetes, Obesity, and Metabolism’s Rodent Metabolic Phenotyping Core. This role involves strategic planning and day-to-day oversight of core staff who perform complex in vivo studies in rodent models for various clients, both internal and external to the University of Pennsylvania. The manager will be responsible for training and supervising research specialists and technicians, developing protocols, ensuring proper technique execution, managing equipment and data collection systems, and overseeing data analysis. The position requires establishing expertise in both technical and theoretical aspects of core assays, including metabolic clamps, indirect calorimetry, telemetry, bomb calorimetry, DEXA, and EchoMRI. Additionally, the Research Manager will manage the service center budget, including pricing and revenue/expense projections, order and maintain lab supplies, coordinate rodent transfers, and prepare various reports (financial, regulatory, technical progress). They will also directly perform and analyze assays in rodent models and troubleshoot equipment/software issues. The role supports animal research on campus and involves consultation with investigators on experimental design.

Requirements

Bachelor of Science/Arts and 5 to 7 years of experience or equivalent combination of education and experience.
Ability to perform complex in vivo studies in rodent models.
Expertise in both the technical and theoretical aspects of core assays including metabolic clamps, indirect calorimetry, telemetry, bomb calorimetry, DEXA, EchoMRI.
Ability to plan and manage service center budget.
Ability to order and manage lab supplies and coordinate rodent transfers.
Ability to prepare financial, regulatory, and technical progress reports.
Ability to maintain core usage data.
Ability to directly perform and analyze assays in rodent models (Body composition (NMR; DEXA); CLAMS; treadmill exercise insulin/glucose clamp and radioisotopic tracer kinetics; thermography; BAT thermogenesis; tissue chemistry; ELISA; Glucose and insulin tolerance tests).
Ability to interface with companies and Penn IT to troubleshoot equipment and software issues.
Ability to consult with internal and external investigators on the selection and design of experimental approaches.

Nice To Haves

Master's degree or PhD.

Responsibilities

Take primary responsibility for the strategic planning and day to day management of core staff performing complex in vivo studies in rodent models for core clients.
Train and serve as the direct supervisor for Research Specialists and Technicians in the core, and serve as the liaison between the director or core clients and the other staff.
Develop protocols, ensuring that techniques are performed properly, managing equipment and data collection systems, and ensuring that data analysis is performed according to accepted practices.
Establish expertise in both the technical and theoretical aspects of core assays including metabolic clamps, indirect calorimetry, telemetry, bomb calorimetry, DEXA, EchoMRI and other services as needed.
Plan and manage service center budget, including evaluation and setting of prices and projecting future revenue and expenses in collaboration with multiple client labs.
Order and manage lab supplies and coordinate rodent transfers to ensure that all necessary resources are in place for core experiments.
Prepare financial, regulatory, and technical progress reports.
Maintain core usage data for reporting to the Core Director, Penn IDOM, NIH and other agencies.
Assist with drafting of grants and/or articles for publication.
Directly perform and analyze assays in rodent models: Body composition (NMR; DEXA); CLAMS; treadmill exercise insulin/glucose clamp and radioisotopic tracer kinetics; thermography; BAT thermogenesis; tissue chemistry; ELISA; Glucose and insulin tolerance tests.
Interface with companies and Penn IT to troubleshoot equipment and software issues, often on the fly, and ensure the smooth operation of the core.
Perform additional duties as needed and assigned to support animal research on campus, including consultation with internal and external investigators on the selection and design of experimental approaches.
Provide daily management for all activities in the Rodent Phenotyping Core.
Design and perform metabolic studies in mouse models, and chemical and immunoassays on tissues.
Analyze assay results and communicate results to investigators.
Maintain core usage statistics for reporting purposes.
Collaborate with the Core director for long range planning.
Develop, implement and monitor lab safety guidelines and procedures.
Oversee lab facilities.

Benefits

Comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits.
Flexible spending accounts to pay for eligible health care and dependent care expenses with pre-tax dollars.
Tuition assistance for employees, spouses, and dependent children at Penn.
Tuition assistance for dependent children at other institutions.
Generous retirement plans (Basic, Matching, and Supplemental) with pre-tax or Roth basis options.
Wide variety of investment options through TIAA and Vanguard.
Substantial amount of time away from work (relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family).
Long-term care insurance (in partnership with Genworth Financial) for faculty and staff and eligible family members.
Wide variety of programs and resources to help care for health, family, and work-life balance.
Array of resources to help advance personally and professionally.
Access to a wide range of University resources, cultural and recreational activities (libraries, athletic facilities, arboretum, art galleries, Penn Museum, Annenberg Center, Penn Relays).
Discounts and special services (arts and entertainment, transportation, mortgages, new cars from Ford and General Motors, cellular phone service plans, movie tickets, admission to theme parks).
Flexible work options (non-traditional work hours, locations, and/or job structures).
Forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia (for closing costs or home improvements).
Reimbursement for qualified expenses in connection with the legal adoption of an eligible child (up to two adoptions).