Research Associate Co-Op, In Vivo Bone Pharmacology
About The Position
At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients. Job Summary We are looking for a highly motivated and innovative student to join the cardiopulmonary and bone team for a 6-month co-op role in our preclinical research group focusing on cardiovascular abnormalities and rare bone diseases. This is a fantastic opportunity to make a significant impact on the discovery and development of next-generation therapies. The candidate will gain valuable industry experience and receive extensive training in vivo and ex vivo research. In addition, a successful candidate will be inquisitive about science and capable of troubleshooting by reviewing literature/colleagues and designing experiments to test hypotheses.
Requirements
- Physiology, biology, biochemistry and molecular biology experience.
- Ability to work as part of a cross-functional team as well as independently with supervision.
- Excellent communication and organization skills, good working knowledge of MS office, and data plotting.
- Students with a major in physiology, biology, biochemistry, or related majors
Nice To Haves
- Interest in cardiovascular and bone physiology
- Prior experience with laboratory animals (rodents), open to learning and perfecting rodent handling and dosing techniques
- Familiarity with basic molecular biology techniques including RNA isolation, qPCR, Western Blot, ELISA
- Experience working with imaging and image analysis such as DEXA and microCT is a plus
Responsibilities
- Supporting In Vivo studies: willingness to work with rodents. This includes animal handling, dosing (IP/IV/SC/PO), bleeding, necropsy, tissue collection and wet lab sample processing
- Basic molecular biology techniques: RNA isolation, qPCR, Western Blot, ELISA
- Maintain detailed and accurate records of experimental procedures, results, and analysis in laboratory notebooks
- Participate in experimental planning, interpretation of data and present findings at team meetings
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What This Job Offers
Career Level
Intern
