R&D Intern

Legend Biotech US • Philadelphia, PA

23h • Onsite

About The Position

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.
Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.
Legend Biotech is seeking a R&D Intern as part of the Research & Early Development team based in Philadelphia, PA.
Role Overview
The R&D Intern will support research activities focused on cellular therapy and CAR-T technology. This role involves analyzing cytotoxic potential of CAR-T cells and other immune cells, performing cytokine analysis, and correlating donor variability. The intern will also assist in evaluating T cells generated with in-vivo CAR platforms and contribute to data analysis and reporting.

Requirements

• College student (BS, MS, or PhD) in Life Science, Biomedical Science, Biotechnology, Cell Science, Biology, Virology, Molecular Biology, or STEM.
• Desired Academic Grade Level: Junior/Senior/ Graduate Student.
• Interest in cellular therapy and immunotherapy.
• Knowledge of CAR-T, virus design, or immune cell assays preferred.
• Ability to commit to lab bench work (70%) and desk work (30%).
• Strong communication and organization skills.

Nice To Haves

• Knowledge of CAR-T, virus design, or immune cell assays preferred.

Responsibilities

• Perform cytotoxicity assays and cytokine analysis using MSD assay.
• Analyze CAR-T cells, macrophages, and other immune cells for cytotoxic potential.
• Correlate cytotoxicity data across multiple donors.
• Support in-vivo CAR platform evaluations.
• Analyze experimental data and prepare reports for manager and team.
• Maintain accurate laboratory records and follow SOPs.

Benefits

• We are committed to creating a workplace where employees can thrive - both professionally and personally. To attract and retain top talent in a highly competitive industry, we offer a best-in-class benefits package that supports well-being, financial stability, and long-term career growth. Our offerings are designed to meet the diverse needs of our team members and their families, ensuring they feel valued and supported every step of the way. Highlights include medical, dental, and vision insurance as well as a 401(k)-retirement plan with company match that vest fully on day one. Equity and stock options are available to employees in eligible roles. We offer eight weeks of paid parental leave after just three months of employment, and a paid time off policy that includes vacation days, personal days, sick time, 11 company holidays, and 3 floating holidays. Additional benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs - demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work. Please note: These benefits are offered exclusively to permanent employees. Contract employees are not eligible for benefits through Legend Biotech.

What This Job Offers

• Career Level: Intern
• Number of Employees: 1,001-5,000 employees