Protein Sciences and Lead Discovery Co-Op
About The Position
Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn. We are seeking a talented and enthusiastic co-op student to join the Protein Sciences and Lead Discovery (PSLD) team at Kymera. This person will gain industry-relevant experience through assisting cross-functional teams with compound screening and biochemical/biophysical assay development on early-stage projects. The ideal candidate is a highly-motivated self-starter, an agile learner, collaborative, and looking to transform patient’s lives through the development of novel therapeutics.
Requirements
- Currently pursuing a BS or MS degree in chemistry, biology, biochemistry, biophysics, biotechnology, or a related field.
- Hands-on laboratory experience in protein science, biochemistry, biophysics, or related fields. Prior exposure to fluorescence-based techniques, running assays in 384/1536-well format, and protein sciences a plus.
- Ability to work well independently in a collaborative team environment. Comfortable in presenting results to small groups and cross-function teams.
- Ability to be onsite in Watertown, Ma July - December 2026 (start/end dates are flexible)
Responsibilities
- Development and validation of fluorescence-based biochemical and biophysical assays to characterize protein-compound and/or protein-protein interactions.
- Assist in the discovery of chemical starting points for early-stage projects using screening technologies, including but not limited to DNA-encoded libraries, automated high-throughput fluorescence or activity-based assays, and fragment-based methods.
- Assist in the validation of screening hits using a suite of technologies including surface plasmon resonance (SPR), isothermal titration calorimetry (ITC), thermal shift assays, dynamic light scattering, time-resolved FRET or fluorescence polarization-based assays, and NMR.
- Work with contract research organizations to oversee generation of protein reagents to facilitate biochemical/biophysical experiments.
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What This Job Offers
Career Level
Intern
Number of Employees
101-250 employees
