Scientist – Antibody Discovery/Protein Engineering

Eurofins•Saint Charles, MO

4d•Onsite

About The Position

The Scientist Antibody Discovery/Protein Engineering will support the Eurofins Discovery Biotherapeutics business in contract research services. This role requires experience and proven knowledge in construct design, antibody formatting and data mining methods with related experience in a contract research organization (CRO) or industry laboratory. Scientist – Antibody Discovery/Protein Engineering responsibilities include, but are not limited to, the following: Performs work in a laboratory setting, meeting the physical job requirements of a lab role Conducts production assays primarily in Biotherapeutics Discovery, but may support other Services and activities based on business needs Contributes to biologics discovery programs Develops and performs assays for Biotherapeutics discovery applications Writes and maintains SOPs as required Develops new methods supporting project teams both internally and externally for large molecule discovery, characterization, and optimization Performs Troubleshooting and Maintenance of equipment employed in the screening process (e.g. liquid handlers, stackers, plate washers, readers) Prepares and manages inventory of buffers, reagents, semi-finished and finished goods. Provides solutions to complex problems, identifies and initiates process improvements Maintains high data quality and reproducibility Performs data and report QC review within the department, and may support study director activities Takes ownership of client projects with minimal supervision Supports validation of new methods, and contributes to expansion of service/product line, equipment, and data management systems Completes required training and supports 100% of Employee Health and Safety requirements Demonstrates proficiency with care and maintenance of lab equipment and department assets Conducts responsible use of confidential IT and business systems, as required Adheres to department SOPs and documentation requirements, maintains accurate data management and reporting Supports unit goals and demonstrates Eurofins’ competencies, as defined in the job plan Provides training to colleagues and external end users, when required Contributes to scientific community, and site research and development objectives Works effectively in a team environment, under minimum direction, to achieve business production, project timelines, and quality objectives Adjusts work hours and provides cross-functional support to other departments, as required, and maintains accountability in delivering to client needs/timelines Routinely communicates project updates to internal and external clients Performs other duties, as assigned

Requirements

B.S. with 5 years relevant experience
M.S. with 3 years relevant experience
Ph.D. with 0 years post-doctoral experience
Direct experience with construct design (antibody and non-antibody proteins), preferably in a contract research organization or industry laboratory, for large molecule discovery applications
Direct experience with antibody discovery methodology
Familiarity with concepts of extracting data from the literature and FTO
Demonstrated proficiency in contributing independently on a project team with time and quality deliverables
Good communication and interpersonal skills
Experience working in a Quality Management System
Scientific expertise with antibody discovery methodology
Scientific expertise with different types of protein design, optimization and production
Scientific expertise in protein production, purification and QC of proteins (antibody and non-antibody)
Scientific expertise with construct design for cell line development
Familiarity with mining public or non-public resources of antibody analysis (immunogenicity, stability, solubility etc.) for antibody engineering and design
Background knowledge of sequence-structure-function correlation
Experience in leading and delivering results in R&D or innovation programs
Authorization to work in the United States indefinitely without restriction or sponsorship.

Nice To Haves

Ability to read, write, and interpret documents, such as standard operating procedures and technical reports
Ability to perform mathematical calculations, statistical analyses, and data interpretation
Ability to multitask with organization and manage time effectively
Ability to solve practical problems and troubleshooting skills
Ability to work in a laboratory setting, according to physical requirements of a laboratory role
Lab equipment and office computer/software proficiency
Above-average oral and written communication skills
Demonstrates a positive attitude, capacity for team environment, and exhibits a genuine interest in drug discovery in support of advancing human health
Ability to develop new methods, and lead research and development projects
Ability to review and QC release data/reports
Ability to lead small, informal sub-teams and train new team members
Ability to conduct mid-size projects with minimal supervision
Ability to contribute to strategic vision, establishment of new service lines, equipment, and data management systems
Ability to easily support cross-functional demands

Responsibilities

Performs work in a laboratory setting, meeting the physical job requirements of a lab role
Conducts production assays primarily in Biotherapeutics Discovery, but may support other Services and activities based on business needs
Contributes to biologics discovery programs
Develops and performs assays for Biotherapeutics discovery applications
Writes and maintains SOPs as required
Develops new methods supporting project teams both internally and externally for large molecule discovery, characterization, and optimization
Performs Troubleshooting and Maintenance of equipment employed in the screening process (e.g. liquid handlers, stackers, plate washers, readers)
Prepares and manages inventory of buffers, reagents, semi-finished and finished goods.
Provides solutions to complex problems, identifies and initiates process improvements
Maintains high data quality and reproducibility
Performs data and report QC review within the department, and may support study director activities
Takes ownership of client projects with minimal supervision
Supports validation of new methods, and contributes to expansion of service/product line, equipment, and data management systems
Completes required training and supports 100% of Employee Health and Safety requirements
Demonstrates proficiency with care and maintenance of lab equipment and department assets
Conducts responsible use of confidential IT and business systems, as required
Adheres to department SOPs and documentation requirements, maintains accurate data management and reporting
Supports unit goals and demonstrates Eurofins’ competencies, as defined in the job plan
Provides training to colleagues and external end users, when required
Contributes to scientific community, and site research and development objectives
Works effectively in a team environment, under minimum direction, to achieve business production, project timelines, and quality objectives
Adjusts work hours and provides cross-functional support to other departments, as required, and maintains accountability in delivering to client needs/timelines
Routinely communicates project updates to internal and external clients
Performs other duties, as assigned

Benefits

Excellent full-time benefits including comprehensive medical coverage, dental, and vision options
Life and disability insurance
401(k) with company match
Paid vacation and holidays

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