Principal Product Manager

Flagship Pioneering, Inc.•Cambridge, MA

13h•$150,000 - $210,000

About The Position

Pioneering Intelligence builds on Flagship Pioneering’s legacy of founding cutting-edge science and computational ventures, harnessing recent advances in AI, machine learning, and data to accelerate fundamental research and create a portfolio of AI-first companies. As part of Flagship’s integrated model of science, entrepreneurship, and capital, it transforms breakthrough ideas into world-changing companies, elevating the AI advances happening across the ecosystem in human health, sustainability, and beyond. Pioneering Intelligence is a strategic initiative of Flagship Pioneering committed to positioning Flagship at the forefront of global prosperity through the synthesis of human, machine, and nature’s intelligence -- which we call Polyintelligence. Pioneering Intelligence is seeking a Senior Product Manager to partner across UX, AI research, engineering, legal, communications and marketing, multi-disciplinary scientific groups and venture creation teams to solve the most impactful challenges in AI for the life sciences. We are building a next-generation digital foundation that integrates computational science, AI/ML, knowledge engineering, data platforms, and workflow automation. These capabilities support Flagship’s unique model of exploring the unknown and translating scientific insight into world-changing companies. The Principal Product Manager, Agentic AI is an individual contributor who owns a product area end-to-end, translating complex user and scientific needs into clear strategy, measurable outcomes, and adopted solutions in alignment with business outcomes. As part of a multidisciplinary team, you will work closely with scientists and business stakeholders to drive impact from agentic systems that reimagine workflows and business capabilities in a fast-moving startup environment.

Requirements

Minimum 7+ years of experience with biotech or life sciences product management
Demonstrated evidence-based, user-centered decision making
Experience leading product strategy development and continuous discovery methods
Ownership mindset with bias toward action
Management of complex stakeholder environment
Prioritize effectively under ambiguity

Nice To Haves

Durg Discovery program development and/or clinical development experience
Demonstrated experience shipping AI-powered products
Familiarity with agentic workflows, automated systems and/or decision support systems
Experience prototyping adaptive interfaces to validate direction and working in an AI research heavy product environment
Comfort working in fast-changing environments

Responsibilities

Own product vision, strategy, and roadmap
Define OKRs and drive measurable outcomes
Lead discovery with scientists, research, synthesize insights, create wireframes
Drive cross-functional decisions and alignment across ML, engineering and scientific stakeholders
Drive adoption, including lead user enablement programs