Preclinical Scientist

Legend Biotech US • Somerset, NJ

12h

About The Position

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.
Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.
Legend Biotech is seeking a Preclinical Scientist as part of the Research and Early Development team based in Somerset, NJ.
Role Overview
This position will perform preclinical IND-enabling pharmacology and toxicology studies to support pipeline programs. The ideal candidate will have experience in immunology or immune-oncology to assist preclinical cell therapy studies from discovery to first-in-human trials, and through marketing authorization. Furthermore, the successful candidate will work in a collaborative environment , and would be skillful in driving multiple projects by contributing to the development of cell-based immunotherapies.

Requirements

• The Preclinical Scientist will work independently reporting directly to the Director of Preclinical Pharmacology and Toxicology.
• The Preclinical Scientist will demonstrate competency and professionalism especially as it pertains to using the scientific method to design, execute, and troubleshoot in vitro laboratory experiments.

Responsibilities

• Develop and validate assays to support diverse projects from lead optimization to the conduct of preclinical pharmacology and toxicology studies for regulatory submission. This includes, designing, optimizing, and implementing IND-enabling studies, contributing to the creation, review, and approval of prospective standard operating procedures, executing in vitro and in vivo IND-enabling studies, recording all experiments in an electronic laboratory notebook, reporting any deviations, analyzing and reporting processed data in the form of a study report.
• Design and support in vitro IND-enabling studies to assess efficacy and safety of cell therapies.
• Support the preparation of scientific and regulatory documents of IND-enabling preclinical studies.

Benefits

• Medical, dental, and vision insurance as well as a 401(k) retirement plan with a company match that vests fully on day one.
• We offer eight (8) weeks of paid parental leave after just three (3) months of employment, and a paid time off policy that includes vacation time, personal time, sick time, floating holidays, and eleven (11) company holidays.
• Additional voluntary benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance.
• We also provide voluntary commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: No Education Listed