Senior Scientist, CGT Preclinical

Pharmaron • Carlsbad, CA

1d • Onsite

About The Position

Pharmaron is seeking a Senior Scientist – CGT Preclinical to support the design, execution, and interpretation of in vivo studies for cell and gene therapy programs.
This role will serve as a Study Director and scientific lead, focusing on toxicology, pharmacology, and biodistribution studies across therapeutic areas including CNS and oncology. The successful candidate will collaborate with internal teams and external sponsors to ensure studies are scientifically robust, operationally efficient, and compliant with regulatory standards.
This position offers the opportunity to contribute to innovative preclinical research in a fast-paced CRO environment while supporting the development of advanced therapies.

Requirements

• D. in Pharmacology, Toxicology, Immunology, or related scientific discipline
• 3+ years of industry experience in preclinical in vivo research (CRO experience preferred)
• Demonstrated experience as a Study Director or scientific lead
• Strong technical expertise in: CNS and/or oncology in vivo models Surgical procedures (e.g., stereotaxic injections) CGT-related preclinical systems
• Experience preparing GLP-compliant protocols, reports, and regulatory documentation
• Knowledge of regulatory standards (FDA, USDA, AAALAC)
• Excellent communication skills with experience interacting with external sponsors
• Ability to thrive in a fast-paced, matrixed environment

Responsibilities

• Serve as Study Director, leading the design, execution, analysis, and reporting of in vivo preclinical studies
• Drive scientific strategy across toxicology, pharmacology, and biodistribution programs
• Partner with sponsors to develop scientifically robust and cost-effective study designs
• Collaborate with in vivo operations, veterinary staff, and QA/QC teams to ensure efficient study execution
• Prepare and review GLP-compliant study protocols, IACUC documentation, and final reports
• Provide subject matter expertise in CNS and oncology models, including immunocompromised systems
• Perform and guide complex in vivo procedures, including stereotaxic injections and advanced dosing techniques
• Ensure compliance with regulatory standards (USDA, FDA, AAALAC, OSHA)
• Maintain accurate study records and contribute to internal database systems

Benefits

• Insurance including Medical, Dental & Vision with significant employer contributions
• Employer-funded Health Reimbursement Account
• Healthcare & Dependent Care Flexible Spending Accounts
• 100% Employer-paid Employee Life and AD&D Insurance, Short- and Long-Term Disability Insurance
• 401k plan with generous employer match
• Access to an Employee Assistance Program

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees