Postdoctoral Fellow-MSH-32035-051
About The Position
The lab of Dr. Romina Bevacqua, an early-career Principal Investigator in the Diabetes,Obesity and Metabolism Institute, is seeking a curious, motivated, Postdoctoral Fellow interested in performingtransformative research on human diabetes and pancreatic islet biology. The broader significance of the work in Bevacqua Lab is that diabetes affects over 400 million people worldwide and advancing our understanding of adult human islet functionality, will lead to development of novel approaches for the treatment of diabetic patients. Morespecifically, Bevacqua Lab is interested in studying: 1) the regulatory mechanisms driving human islet maturation: 2)the genetic basis for their dysregulation in disease: and, 3) the application of these findings towards β-cellregeneration and replacement therapies. These approaches will include implementation of novel genetic approaches in vivo to reverse diabetes, and will open new possibilities for the treatment of patients with diabetes. To address these topics, the lab uses cellular biology, including genetics on pseudoislet organoids derived from non-diving human islets, molecular biology, Next-gen sequencing (CUT&RUN, RNA-seq, ATAC-seq, Mi-seq), FACS of different islet cell populations, functional studies, islet transplantation approaches, and imaging. The selected candidate for this full-time position will be expected to apply well-established protocols and develop novel ones to address basic or translational research questions in diverse areas of pancreatic islet cell biology,including diverse NGS technologies, CRISPR screenings and novel CRISPR -or similar- genetic approaches. This postdoctoral opportunity will enable training in development of cutting-edge experimental methods. Theselected candidate will have the opportunity to participate in collaborative projects with multiple institutions fromNorth America and Europe.
Requirements
- Qualified candidates should be self-driven and independent
- enthusiastic for team work
- eager to work in afriendly environment
- track record of success supported by first-author publications in related fields
- strong interest in basic and translational diabetes research
Responsibilities
- apply well-established protocols
- develop novel ones to address basic or translational research questions in diverse areas of pancreatic islet cell biology
- participate in collaborative projects with multiple institutions from North America and Europe
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What This Job Offers
Job Type
Full-time
Education Level
Ph.D. or professional degree
