Postdoctoral Fellow - Prajwal Rajappa Lab

Cleveland Clinic

2d • Onsite

About The Position

At Cleveland Clinic Health System, we believe in a better future for healthcare. And each of us is responsible for honoring our commitment to excellence, pushing the boundaries and transforming the patient experience, every day. We all have the power to help, heal and change lives — beginning with our own. That’s the power of the Cleveland Clinic Health System team, and The Power of Every One. Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. This training position, under the direct supervision of a Cleveland Clinic Principal Investigator will provide practical training and experience in a research setting. This position is appointed through Cleveland Clinic Research. The successful applicant will be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. This program is expected to be completed within 5 years.
Our translational laboratory is dedicated to bridging the gap between bench and bedside by developing innovative cellular immunotherapies for children and young adults with gliomas and other CNS tumors. We are particularly focused on integrating personalized medicine and immunotherapy as an addition to the standard of care to improve survival and quality of life for our patients. Principal Investigator: Prajwal Rajappa, MD, MS Cleveland Clinic Research Department: Center for Immunotherapy and ImmunoOncology/ Cancer Sciences Lab Research Topics: Pediatric and Adolescent and Young Adult (AYA) brain cancer Glioma and Central nervous system (CNS) tumor and immune biology Innate (myeloid) and adaptive immunity within the glioma immune microenvironment Personalized medicine Cellular immunotherapy For more information about the lab’s research, please contact Dr. Rajappa at [email protected].

Requirements

• PhD or MD/PhD required
• MD with relevant laboratory experience may substitute for PhD
• English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa status
• Previous experience in a research or academic setting.
• Graduate student experience meets this requirement.
• Scientific writing experience

Nice To Haves

• Strong background in cancer biology or tumor immunology
• Experience with molecular biology techniques and mouse modeling (in-vivo handling and treatment studies in mouse tumor model systems)
• Experience with multi-parameter flow cytometry, myeloid, NK, and T cell-based assays for human and mouse samples
• Experience working with the interpretation of next-generation sequencing data
• Strong publication record in addition to excellent communication and teamwork skills

Responsibilities

• Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation
• Conduct translational research focused on Pediatric and Adolescent and Young Adult (AYA) Gliomas and Central Nervous System tumors
• Design and implement cellular immunotherapy strategies to prevent glioma progression
• Develop and evaluate personalized medicine approaches to complement standard of care
• Leverage unique human and mouse archival tissues to advance research and clinical impact

What This Job Offers

• Career Level: Entry Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees