Manager, Payroll and Benefits

Tenpoint Therapeutics, Ltd.

2d•Hybrid

About The Position

We are seeking a Manager, Payroll & Benefits who can dive into the details while also shaping the big picture. You’ll ensure our employees across the U.S. (multi-state), U.K., and Switzerland are paid accurately and on time, supported by robust benefits programs, and confident that their data is managed with integrity. This role is both hands-on and strategic: you’ll run payroll, administer benefits, and manage HRIS data while also designing scalable processes, anticipating the needs of a growing global workforce, and partnering with Finance, HR, and vendors to strengthen compliance and efficiency. You’ll also help ensure we remain audit-ready and well-prepared as we move toward commercial launch and the expectations of a future public company.

Requirements

Prior experience running payroll for organizations of 200+ employees across multiple U.S. states is required.
Strong knowledge of multi-state U.S. payroll and benefits; U.K. and/or Swiss payroll/benefits experience a plus.
5+ years of payroll and benefits experience, ideally with multi-country exposure.
Hands-on experience with Rippling (or another HRIS/payroll system) and proven ability to maintain HRIS data integrity.
Familiarity with journal entry preparation, payroll reconciliations, and retirement/pension administration.
Experience ensuring audit readiness and supporting high-growth environments preparing for commercial scale-up.
Knowledge of workers’ comp programs and I-9 verification compliance.
Ability to balance day-to-day execution with strategic planning.
Experience managing vendors and holding them accountable for service excellence.
Strong analytical, organizational, and communication skills.
Comfort working in a fast-paced, scaling, global environment

Responsibilities

Run multi-state U.S. payroll and U.K. payroll directly through Rippling, ensuring accuracy, timeliness, and compliance across local, state, federal, and international regulations.
Oversee Swiss payroll via a third-party vendor, ensuring service quality and preparing for eventual in-house transition.
Reconcile payroll reports and prepare journal entries for Finance, ensuring accurate postings to the general ledger.
Manage year-end payroll activities (W-2s, P60s, tax filings, and other statutory reports), including the accurate treatment of vehicle allowances, stipends, and other taxable fringe benefits.
Administer U.S. retirement plan contributions and U.K. pension fund allocations, ensuring accurate transfers, reconciliations, and compliance.
Maintain workers’ compensation compliance, including proper state setup, reporting, employee classifications, and coordination of annual audits with carriers and brokers.
Ensure I-9 employment verification compliance, including accurate documentation, timely reverifications, and audit readiness.
Proactively build processes to support payroll expansion into new geographies as we scale.
Maintain audit-ready documentation and scalable practices.
Administer employee benefits in the U.S., U.K., and Switzerland, including health, dental, vision, life, disability, retirement/pension, and wellness programs.
Partner with brokers and vendors to evaluate programs, recommend enhancements, and ensure offerings remain competitive and aligned with our culture.
Provide responsive support for employee questions while also helping plan for the evolving needs of a global workforce.
Ensure compliance with ERISA, ACA, GDPR, and other applicable frameworks
Maintain accurate employee records in Rippling, ensuring timely entry, compliance, and data integrity.
Build and deliver reports and dashboards for HR, Finance, and leadership to support planning, audits, and decision-making.
Partner with HR, Finance, and IT to maintain seamless data flows between systems and ensure audit-ready reporting for compliance and regulatory compliance.
Identify opportunities to streamline and automate payroll and benefits operations for efficiency and employee experience.
Develop scalable policies, documentation, and practices to support rapid growth and global expansion.
Stay ahead of employment law and regulatory changes across all jurisdictions, ensuring compliance and readiness for future milestones such as commercial launch and IPO preparation.
Collaborate cross-functionally with HR, Finance, IT, and Compliance to strengthen controls and reduce risk.