Lipid Nanoparticle & mRNA Synthesis Intern

Sartorius Stedim • Marlborough, MA

13d • Onsite

About The Position

Sartorius has an onsite position available for a Research Intern (Lipid Nanoparticle & mRNA Synthesis) at our Marlborough, MA site. In this role, you will contribute to the full product development cycle-from concept to prototype-and collaborate closely with engineers and scientists in a multidisciplinary environment. Sartorius is a leading technology provider to the life sciences and biopharma industries, actively shaping dynamic, innovative, and high‑growth markets. To drive the creation of new solutions, Sartorius has formed a global Corporate Research initiative that identifies emerging trends and rapidly translates them into next‑generation technology solutions. As part of our team in Marlborough, we are seeking a highly motivated intern with a multidisciplinary background in biomedical and bioengineering. Onsite role based at our Marlborough, MA site

Requirements

• Education PhD graduate or student in biomedical, chemical, mechanical engineering, or related field with formal education and experience with lipid nanoparticles and/or nucleic acids.
• Experience Hands-on laboratory work including mammalian cell culture and handling of RNA.
• Experience with LNP formulation characterization techniques and biological assays used to evaluate key LNP properties
• Strong oral and written communication and presentation skills.
• Identification with our core values: Sustainability, Openness, Enjoyment

Nice To Haves

• Ideal to have an experience with one or more of the following: dynamic light scattering (DLS), nanoparticle tracking analysis, RiboGreen assay, HPLC
• Familiarity with nanoparticle formulation, microfluidics instruments, laboratory automation, chromatography (AKTA), advanced cell models, in vivo animal models, and in vitro transcription is plus.

Responsibilities

• Establish, execute, and maintain protocols for the preparation and characterization of lipid nanoparticle (LNP) formulations encapsulating nucleic acid cargo using automated LNP synthesis platforms.
• Perform in vitro assays to assess transfection efficiency and delivery of nucleic acids using formulated LNPs in mammalian cell systems.
• Conduct systematic experiments of in vitro transcription (IVT) reaction on benchtop bioreactors; collect and analyze the data.
• Support process development activities for LNP screening, scale-up, and manufacturing-relevant workflows.
• Troubleshoot issues with experimental design and execution.
• Collect, analyze, and interpret experimental data; prepare technical summaries and present results in internal meetings and reviews.

Benefits

• Personal and Professional Development: Mentoring, leadership programs, internal seminar offerings
• Making an Impact Right from the Start: Comprehensive onboarding, including a virtual online platform
• Welcoming Culture: Mutual support, team spirit and international collaboration; communities on numerous topics such as “Coaching”, “Agile Working” and a “Businesswomen’s Network”
• Intelligent Working Environment: Working in smart buildings with the latest technology and equipment.

What This Job Offers

• Career Level: Intern
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees