Lead Reagent Manufacturing Associate

BillionToOne • Union City, CA

7d • Onsite

About The Position

Ready to redefine what's possible in molecular diagnostics?
Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.
Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.
Lead Reagent Manufacturing Associate, BillionToOne, Inc., Union City, CA. Responsible for the manufacturing, assembly, and qualification of reagents in support of the Clinical Laboratory. Will also be responsible for: the troubleshooting of reagent manufacturing activities and management of sufficient reagent inventory within the Clinical Laboratory; Managing and performing the training of new operators on established reagent manufacturing methods; Authoring and executing formal deviations, verifications, and validations to support changes in the manufacturing process; Developing novel, robust manufacturing or qualification techniques independently or through collaboration with development teams; and leading inventory management of reagents used in and prepared by Reagent Manufacturing through preparation and maintenance of build schedules. Position requires supervision of other employees. Telecommuting permitted up to fifteen working days per quarter.
BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA,a breakthrough that has already transformed the lives of over half a million patients worldwide.
Our Impact
Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.
Our Growth
From $0 to $150M+ in Annual Recurring Revenue in just five years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.
Our Recognition
Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.
Our Future
Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.
Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com

Requirements

• Bachelor’s degree in biology, chemistry, biochemistry, chemical engineering, or a related life sciences field and 2 years of experience as a Reagent Technician, Reagent Associate, Clinical Lab Associate or Research Associate
• 2 years of experience in a high complexity laboratory environment
• 2 years of experience with molecular biology techniques (ex. PCR and DNA sequencing)
• 1 year of experience with analyzing and problem-solving issues that impact reagent manufacturing and qualification events
• 1 year of experience with laboratory automation platforms
• Must successfully complete competency-based interview

Responsibilities

• Manufacturing, assembly, and qualification of reagents in support of the Clinical Laboratory
• Troubleshooting of reagent manufacturing activities and management of sufficient reagent inventory within the Clinical Laboratory
• Managing and performing the training of new operators on established reagent manufacturing methods
• Authoring and executing formal deviations, verifications, and validations to support changes in the manufacturing process
• Developing novel, robust manufacturing or qualification techniques independently or through collaboration with development teams
• Leading inventory management of reagents used in and prepared by Reagent Manufacturing through preparation and maintenance of build schedules

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 251-500 employees