Open Rank Laboratory Sciences Professional (Entry – Intermediate) – Cardiology Research

University of Colorado•Aurora, CO

1d•Onsite

About The Position

Our laboratory is truly translational. By leveraging biobanked human samples, we employ numerous mouse models to dissect heart transplant rejection. We have a microsurgeon to perform heart transplants in mice, a rare opportunity to work with this model system. Our system has direct translatability to patient care. Our lab works with cutting-edge technologies and has been and will continue to be highly prolific in its publication record. As a member of the lab, you will work alongside a physician-scientist (PI) that is eager and excited to teach and help you advance your career as you learn new skills, gather knowledge, and function as an essential member of the team. We will tailor your experience to your comfort level but anticipate that you will ultimately design and carry out experiments independently. The goal of this job is to be mutually beneficial. You will learn and perform incredible science and will also have the opportunity for authorship and career advancement. As a physician scientist, it is incredibly important for me to foster a scientific environment that will have direct clinical impact. Our lab will be fast-paced and prolific. We will ask questions that clinicians are asking but we have the unique ability to search for these answers. This puts us in an exceptional situation in the biomedical research field. We will leverage this benefit to construct experiments to real time relevant questions. As a candidate, these experiences will not only be intellectually rewarding, but will bolster your academic resume, open the doors to other thought leaders in the field, and provide the confidence to pursue your chosen career path. The University of Colorado, Anschutz Medical Campus combines a top tier environment for ground-breaking research with proximity to a vibrant city and expansive outdoor opportunities! This combination will satisfy your career aspirations and your overall wellbeing. The University of Colorado Denver, Anschutz Medical Campus as a whole, ranks among the top 20 medical centers in the country. CU Anschutz has top-ranked clinical programs in family medicine and pediatrics, and the basic science and applied health research programs attract more NIH funding than any other university in Colorado. The Anschutz Medical Campus is a place of vibrant and collaborative research with multiple opportunities to learn new techniques, explore exciting ideas, and interact with experts in many disciplines. We and others are investigating heart function from an ever-growing array of angles, to develop the critical knowledgebase and infrastructure necessary to identify efficacious therapies to improve outcomes in heart pathologies.

Requirements

Bachelor’s degree in biology, molecular biology, chemistry, genetics, or related field.
One (1) year professional-level research experience (for Intermediate Level).
A combination of education and related technical/military/paraprofessional experience may be substituted for a bachelor’s degree on a year for year basis.
Applicants must meet minimum qualifications at the time of hire.
Proficient knowledge of basic laboratory techniques, including safety procedures and techniques.
Ability to communicate effectively, both in writing and orally.
Ability to establish and maintain effective working relationships with employees at all levels throughout the institution.
Outstanding customer service skills.
Knowledge of basic human anatomy, physiology, and medical terminology.
Ability to interpret and master complex research protocol information.
Training in molecular techniques with a good theoretical understanding and experience in interpretation of results.
Laboratory management skills.

Nice To Haves

Master’s degree in biology, molecular biology, chemistry, genetics or related field.
Two (2) years of experience in an experimental or wet laboratory
Cell culture experience.
Experience laboratory animal management and handling.

Responsibilities

Mouse husbandry and genotyping of complex strain combinations (congenic, lineage tracing, genetic knockouts).
Work alongside surgeon to learn how to assess transplant survival.
Daily administration of critical experimental drugs or placebo.
Heart transplant readouts will include flow cytometry, single cell RNA sequencing, histology, cytotoxicity assays, and immunofluorescence.
Work with the PI and a team of collaborators in an open, enthusiastic, and exciting environment.
Design and carry out experiments independently.