IT Manager , SOX & ITGC Compliance

Repligen Corporation•Waltham, MA

2d•$116,000 - $178,000

About The Position

Make a global impact—join Repligen. We’re united by a mission to inspire advances in bioprocessing as a preferred partner in the production of biologic drugs that improve human health worldwide. No matter your role or background, at Repligen, you will play a key part in shaping some of the most innovative and life-changing therapies in the world. We foster a culture of purpose, collaboration, and shared success—where every voice matters and every contribution drives progress. Join us! IT Manager, SOX & ITGC Compliance We are seeking an experienced IT Manager, SOX & ITGC Compliance to lead the design, implementation, and ongoing effectiveness of internal controls over financial reporting and key digital systems. This role drives the ITGC audit program, advises on risk mitigation strategies, and partners closely with Internal Audit, IT, Financial Reporting, and external auditors to strengthen Repligen’s control environment.

Requirements

8–10 years of hands-on experience in IT Audit, ITGC, or IT Risk Management within a public or large-scale company.
Deep understanding of SOX ITGC requirements and COSO/COBIT frameworks; proven experience designing SOX controls.
Strong knowledge of SAP controls.
Solid understanding of enterprise applications and IT infrastructure (Windows/Linux, ServiceNow).
Experience managing the full audit lifecycle and working with external auditors (Big Four experience a plus).
Familiarity with cloud security controls (AWS, Azure, GCP).
Strong analytical skills with experience identifying control gaps and developing actionable remediation strategies.
Bachelor’s degree required.

Nice To Haves

Preferred (not required): certifications in data management or business intelligence (e.g., CDMP, CBIP).

Responsibilities

Lead the planning, execution, and documentation of SOX IT testing activities, partnering closely with external auditors and co-sourced teams.
Oversee the design, implementation, and testing of IT General Controls, including: Access Management (user provisioning, privileged access, segregation of duties) Change Management (system updates and configuration changes) IT Operations (backup/recovery, job scheduling, incident management) SDLC controls
Coordinate and oversee day-to-day activities of 3rd-party SOX testing partners; escalate issues as needed.
Partner with Digital control owners to ensure timely testing, certifications, and issue resolution.
Train and support control owners to maintain accurate, compliant SOX documentation.
Evaluate the design and operating effectiveness of ITGCs across Logical Access, Change Management, System Operations, and IT Governance.
Conduct IT application control reviews for key systems (e.g., SAP, Tagetik, Workday, ServiceNow).
Provide guidance on control design, new implementations, and remediation activities.
Monitor and track remediation plans for identified control weaknesses.
Serve as SME for system implementations and infrastructure changes to ensure “controls by design.”
Maintain ITGC narratives, process flows, and risk/control matrices.
Identify and drive process improvements, automation opportunities, and standardization across ITGC and SOX processes.
Utilize data analytics to enhance testing quality, reduce risk, and improve audit coverage.
Stay current on regulatory requirements (SOX, GDPR, CCPA) and relevant frameworks (COSO, COBIT, NIST).
Act as the primary liaison with internal teams, Internal Audit, and external auditors.
Communicate risks, findings, and recommendations to both technical and non-technical stakeholders, including senior leadership.

Benefits

We offer a wide range of benefits such as paid time off, health/dental/vision, retirement benefits and flexible spending accounts.
All compensation and benefits information will be confirmed in writing at the time of offer.

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