Global Health Economics & Outcomes Research (HEOR) Associate Director (HYBRID)

Vertex Pharmaceuticals•Boston, MA

6d•$176,000 - $264,000•Hybrid

About The Position

Vertex is a global biotechnology company on the forefront of scientific innovation. In addition to marketed therapies in cystic fibrosis (CF), sickle cell disease, beta-thalassemia, and moderate-to-severe acute pain , our research pipeline spans more than a dozen programs targeting the underlying mechanisms of serious diseases. Vertex is seeking a talented and motivated individual to join its Global Health Economics & Outcomes Research (HEOR) group based in Boston's Seaport District. The HEOR Associate Director will participate in the shaping and execution of HEOR strategies that optimize the value proposition for Vertex’s CF and early pipeline assets through each stage of development, including launch and post-launch phases. This position reports to the Executive Director HEOR, CF and Early Pipeline.

Requirements

Strong track record of publication in peer-reviewed journals
Strong background in clinical outcome assessment (COA) measurement strategy; experience in PRO development/validation and qualitative research methodology
Technical expertise in HEOR with able to formulate and lead creative research projects and ensure conduct is technically and scientifically rigorous and reflects best HEOR practices; hands-on experience with prospective and site-based research is desired
Strong verbal and written communications skills, including presentation skills to communicate difficult concepts and persuade others; comfortable communicating complex concepts and adapting presentation style to a variety of audiences
Excellent project and people management skills to oversee vendors and internal project team, while aligning with cross-functional partners to ensure successful project execution, on timelines and budgets
Ability to apply knowledge of US healthcare system, global health technology appraisal requirements, and clinical development, to identify evidence gaps and formulate evidence generation strategies
Understanding of the legal and regulatory environment of the pharmaceutical industry, with spotless history of compliance and ethical workplace conduct
Advanced degree (PhD, MD, Master's degree, MPH, or PharmD) in a relevant discipline.
Typically requires 8+ years of relevant experience, with substantial background in a Global HEOR role in a pharmaceutical/biotech setting, or the equivalent combination of education and experience

Responsibilities

Leads execution of complex HEOR evidence generation studies, with focus on prospective and retrospective observational studies, COA strategy, and PRO measure development and validation, as well as systematic literature reviews, cost-effective analyses and budget impact models, indirect treatment comparisons, as needed, to support the asset value.
Effectively leads external research partners to ensure robust scientific methods are applied to study design and execution and in compliance with all local regulations; is accountable for study design, data analysis and the quality of the evidence produced.
Excellent project management is a pre-requisite to ensure studies delivered on time and within budget.
Collaborates with the medical communications teams on publication strategy and ensure that dissemination of HEOR evidence is timely and has maximum impact
Partners and works closely with Global Pricing and Market Access to support development of product value proposition/value messaging and co-lead development of robust Global launch deliverables (e.g., global value dossier)

Benefits

This role is eligible for an annual bonus and annual equity awards.
Some roles may also be eligible for overtime pay, in accordance with federal and state requirements.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

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