About The Position

Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Live What you will do Let’s do this. Let’s change the world. In this vital role, the Executive Director, Global In-Line Brands & Global Commercial Execution will provide enterprise-level commercial leadership for a cross-therapeutic portfolio of mature, in-line assets, ensuring sustained value creation through disciplined global strategy, strong market pull-through, and continuous improvement of Amgen’s global-with-local operating model.This role is accountable for maximizing the lifecycle value of assigned brands, shaping global brand strategy in partnership with markets, and ensuring executional excellence, consistency, and focus across regions. Please note 25% international travel is likely.

Requirements

  • Doctorate degree and 6 years of global commercial or marketing experience OR Master’s degree and 10 years of global commercial or marketing experience OR Bachelor’s degree and 12 years of global commercial or marketing experience
  • 6+ years of managerial experience leading people, teams, programs, or enterprise initiatives

Nice To Haves

  • Experience leading global commercial or marketing teams in the biopharmaceutical industry
  • Success managing mature, in-line brands and optimizing lifecycle value
  • Understanding of global-with-local operating models and executional governance
  • Ability to influence senior stakeholders and drive alignment across regions and functions
  • Experience working across multiple therapeutic areas and competitive markets
  • Brings business judgment, prioritization skills, and executive presence
  • MBA or equivalent advanced business training preferred

Responsibilities

  • Portfolio & Brand Leadership Provides commercial leadership across a portfolio of global in-line brands (e.g., Otezla, Prolia, Kyprolis, Nplate, Xgeva, Vectibix) through the full lifecycle
  • Maximizes asset value by guiding brand strategy, prioritization, and investment decisions, including any remaining Patient Impact Expansion (PIE) opportunities
  • Ensures clear global brand positioning and strategic coherence across therapeutic areas and markets
  • Global-With-Local Operating Model Oversees and optimizes the global-with-local commercial execution model, ensuring strong connectivity between global strategy and local execution
  • Partners closely with key markets to co-create brand strategies, balancing global consistency with local market needs
  • Drives focus on the highest-value opportunities and ensure resources are deployed against clear commercial priorities
  • Commercial Execution & Cross-Functional Leadership Leads and influences cross-functional partners across Global Commercial Operations, regions, and therapeutic areas to deliver aligned commercial plans
  • Serves as a key commercial voice in global governance forums, ensuring timely, high-quality commercial input to decision-making
  • Champions best practices, continuous improvement, and disciplined execution across global commercial activities
  • People & Team Leadership Leads and develops a high-impact global team, including: In-Line Global Marketing Directors, accountable for global brand strategy and planning Global Commercial Execution Leads (GCELs) aligned by therapeutic area, accountable for market pull-through and executional excellence
  • Sets clear expectations, fosters collaboration, and builds strong succession and capability pipelines
  • Enterprise Influence Partners with Global Marketing Therapeutic Area VPs to continuously evolve ways of working and strengthen global-local collaboration
  • Builds strong relationships across functions and geographies, influencing without authority in a complex matrix environment
  • Acts as a role model for Amgen leadership behaviors and values

Benefits

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans and bi-annual company-wide shutdowns
  • Flexible work models, including remote work arrangements, where possible

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What This Job Offers

Job Type

Full-time

Career Level

Executive

Education Level

Ph.D. or professional degree

Number of Employees

5,001-10,000 employees

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