Downstream Process Development Engineer, Bioproduction (Plainville, MA)

Thermo Fisher Scientific • Plainville, MA

21d • $96,000 - $127,000 • Onsite

About The Position

This Scientist leads downstream process development and technology enablement using Thermo Fisher’s single-use purification platforms. This role advances our mission of evidence generation, customer training, and process innovation working to accelerate customer adoption and operational excellence. Acting as a technical liaison for customers, R&D, and manufacturing, this position develops scalable, data-driven purification strategies for recombinant proteins and novel modalities. This role drives internal capability-building through structured training, workshops, and mentorship — ensuring Thermo Fisher teams and customers alike can expertly implement guidelines in single-use chromatography and filtration systems.

Requirements

• B.S in Chemical Engineering, Biochemistry, Biotechnology, or related field with ≥5 years of meaningful experience; M.S. with ≥3 years; or PhD
• Proven experience developing, optimizing, and transferring recombinant protein purification processes (chromatography, UF/DF, process characterization).
• Demonstrated proficiency in downstream single-use system implementation and process solving.
• Familiarity with data capture, process automation, and integration of analytics for process insight.
• Advanced knowledge of downstream bioprocess operations and system integration.
• Demonstrated ability to generate technical evidence supporting process robustness and product claims.
• Skilled communicator with experience delivering customer trainings and technical presentations.
• Ability to design and complete sophisticated experimental plans aligned with measurable metrics.
• Strong collaboration skills and comfort operating within a global, matrixed organization.

Responsibilities

• Customer Process Development and Evidence Generation Design and implement purification process development studies across capture, intermediate, and polishing operations.
• Generate high-quality datasets demonstrating system performance, reproducibility, and scalability across Thermo Fisher’s downstream single-use platforms (e.g., Dyna Chrom™, Dyna Spin™).
• Develop and publish robust technical data packages supporting customer confidence and commercial product claims.
• Collaborate with global R&D and product management teams to translate customer use cases into platform enhancements and application notes.
• Customer Engagement and Training Lead hands-on customer training and technology demonstrations focused on chromatography, filtration, and process analytics.
• Deliver engaging training that accelerates adoption of Thermo Fisher’s purification technologies.
• Partner with field and commercial teams to implement customer workshops and data-driven showcases that highlight process performance and reliability.
• Internal Enablement and Capability Building Conduct structured internal workshops and technical upskilling sessions to embed downstream process knowledge within Thermo Fisher teams.
• Mentor emerging scientists and engineers in purification process design, experimental planning, and data analysis.
• Codify downstream guidelines and lessons learned into SOPs, templates, and internal knowledge libraries.
• Technology Innovation and Collaboration Partner with upstream, automation, and analytical colleagues to integrate end-to-end single-use workflows within the BDC.
• Contribute to continuous improvement of purification process automation, data acquisition, and control systems.
• Find opportunities to standardize downstream workflows across customer applications to improve scalability, reproducibility, and time-to-validation.

Benefits

• A choice of national medical and dental plans, and a national vision plan, including health incentive programs
• Employee assistance and family support programs, including commuter benefits and tuition reimbursement
• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
• Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
• Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees