Director of Facilities Operations

Syner-G • San Francisco, CA

14d • $200,000 - $210,000

About The Position

A career here is life-enhancing.
At Syner-G, we enable our people to build careers that impact positively on their quality of life. Through our expertise, insight, consulting and management skills, we accelerate breakthrough science and delivery of life-enhancing therapies to more patients. We work across a diverse range of clients and projects, supporting many organizations from the most critical phases of the drug discovery and approval process through to commercialization. It is meaningful, varied and thought-provoking work with a strategic emphasis, a solutions-driven approach and significant, real-world outcomes, from science to delivery/success.
Underpinning this mission is a culture that aligns perfectly with what we want to achieve. We enable our people to grow, we support them in their learning and we reward them in so many different ways. In return, they play an instrumental role in maintaining our reputation across the globe as a strategic biopharma product development and delivery partner.
Syner-G was recently honored with BioSpace's prestigious "Best Places to Work" 2026 award, for the third consecutive year, along with many other award-winning programs to make a career here truly life-enhancing. These recognitions are a testament to our commitment to fostering a positive and engaging work environment for our employees, with a particular emphasis on culture, career growth and development opportunities, financial rewards, leadership and innovation.
At Syner-G, we recognize that our team members are our most valuable asset. Join us in shaping the future, where your talents are valued, and your contributions make a meaningful impact.
For more information, visit www.Synergbiopharma.com
We are seeking an experienced and strategic Director, Engineering Operations to lead and optimize our engineering infrastructure, with a strong emphasis on laboratory design, setup, and ongoing operational excellence. This role will drive the establishment and scaling of lab facilities to support R&D, testing, and product development, ensuring alignment with organizational goals and regulatory compliance.

Requirements

• Bachelor’s or Master’s degree in Engineering, Operations Management, or a related field
• 10 or more years of experience in engineering operations or technical program management
• 3 to 5 or more years of experience in lab buildout and infrastructure leadership
• Deep understanding of lab safety, infrastructure systems (HVAC, electrical, plumbing), and equipment used in scientific or engineering R&D
• Proven track record of setting up and scaling lab environments in high-growth companies or regulated industries such as biotech, medtech, or semiconductors
• Strong project management and vendor coordination skills
• Excellent communication, leadership, and organizational skills

Nice To Haves

• Experience with GMP/GLP or ISO-certified labs
• Familiarity with CAD or lab planning software
• Lean Six Sigma or similar operational efficiency certification

Responsibilities

• Lead the planning, design, build-out, and commissioning of engineering and R&D lab spaces
• Collaborate with facilities, EH&S, IT, and engineering teams to ensure lab infrastructure (HVAC, electrical, safety, clean rooms, etc.) meets technical and regulatory standards
• Source and manage installation of specialized equipment, instrumentation, and lab utilities such as gas lines, benches, and fume hoods
• Oversee daily engineering operations including equipment uptime, asset management, and lab technician workflows
• Implement and maintain systems for inventory control, sample tracking, maintenance scheduling, and equipment calibration
• Optimize operational processes to improve efficiency, safety, and scalability
• Develop and manage capital and operational budgets for engineering operations and lab buildouts
• Create strategic roadmaps for lab expansion aligned with product development timelines and company growth
• Act as the central liaison between engineering, quality, facilities, and leadership teams
• Support onboarding and training of engineering staff on lab safety, equipment use, and standard operating procedures (SOPs)
• Ensure labs are inspection-ready and compliant with OSHA, ISO, and other relevant standards
• Build and lead a high-performing engineering operations team including lab managers, technicians, and facilities coordinators
• Foster a culture of accountability, continuous improvement, and technical excellence

Benefits

• We define total rewards as compensation, benefits, remote work/flexibility, development, recognition, and our culture with programs that support each of our reward pillars.
• This includes a market competitive base salary and annual incentive plan, robust benefit offerings, and ongoing recognition and career development opportunities.
• Employees also enjoy our generous flexible paid time off program, company-paid holidays, flexible working hours, and fully remote work options for most positions and the ability to work “almost anywhere.”
• However, if a physical work location is more for you, we have office locations in Greater Boston; San Diego, CA; Boulder, CO; and India.

What This Job Offers

• Job Type: Full-time
• Career Level: Director
• Number of Employees: 251-500 employees