About The Position

Earli is a BioAI therapeutics firm in Redwood City, California that programs cancer to turn against itself. Cancer cells become hyperlocal factories for potent immune therapies that are otherwise too toxic to be used systemically . Earli AI-designs synthetic genetic switches that are intravenously injected but ONLY activate in cancer cells, using non-integrating DNA in a stealth LNP. Once activated, they force the cancer cells to produce encoded proteins – T cell engagers, cytokines, agonists – that activate the immune system to kill the cancer. The hyperlocal activation avoids on-target/off-tumor effects and drives up the therapeutic index. Instead of focusing on where the drug goes , Earli changes where the drug is produced . Earli is currently seeking a highly motivated Research Associate/Senior Research Associate to join the Molecular Analysis team as a 4-month contract position . The successful candidate will play a key role in the molecular analysis of the Earli platform technology by supporting efforts to process tissue samples, extract high-quality nucleic acids, and run qPCR and RT-qPCR assays.

Requirements

  • BS degree in Molecular Biology, Biochemistry, or related life sciences field with hands-on molecular biology wet lab experience with 1+ years of experience in an industry setting.
  • Hands-on experience performing nucleic acid extraction from mammalian cells and tissue samples, cDNA synthesis, and quantification using standard molecular methods.
  • Excellent organizational skills and attention to detail, with the ability to manage multiple tasks simultaneously in a fast-paced environment.
  • Effective communication and interpersonal skills, with the ability to work collaboratively in a team setting.

Nice To Haves

  • Experience with organizing and managing a high volume of samples is desired.

Responsibilities

  • Isolate nucleic acids from a wide variety of frozen tissues from animal models using manual and semi-automated methodologies.
  • Assess quality and quantify extracted DNA and RNA
  • Perform cDNA synthesis and qPCR analysis on large numbers of samples at a time (100-150).
  • Maintain detailed electronic lab notebooks and databases, documenting all experimental procedures, sample information, and results with accuracy.
  • Work closely with other research team members to coordinate sample collection, processing, analysis, and interpretation of results.
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