Associate Scientist

Sanofi • Framingham, MA

2d

About The Position

We are looking for candidates for the position of Research Associate in the Bioprocess Engineering Technical Pilot Plant (BPE-TPP) Downstream team. BPE-TPP is responsible for the execution of large-scale manufacturing of biological molecules to support early and late stage development processes and works closely with the Upstream and Downstream development groups. BPE-TPP delivers biological products used in support of early development for First in Human molecules and late stage biological development batches including process confirmation/consistency. TPP supports/executes technology innovations for process improvement working with development groups on innovation projects. Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.
About Sanofi: We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Requirements

• Bachelor’s degree in chemical engineering, chemistry, biochemistry, or related field, with a minimum of 2 years of relevant experience in downstream protein manufacturing processes, ideally at pilot scale.
• Understanding of chromatography modalities such as IEX, HIC, affinity, and multimodal.
• Ability to work within a team and set priorities.

Nice To Haves

• Previous experience in a protein purification lab or pilot plant.
• Familiarity with GMP or GLP.
• Experience operating and troubleshooting downstream unit operations (Columns, UF/DF, TFF, VI, VF).
• Experience with single use downstream technology.
• Demonstrated proficiency in oral and written communication, an innovative problem solver and proven ability to recognize and recommend areas for improvement
• Demonstrated commitment to continuous improvement – at the individual, department and organizational level.
• Ability to effectively interact with a variety of communication and working styles.
• Ability to gown and gain entry to manufacturing areas.
• Ability to work flexible hours if needed.
• High level of scientific curiosity.

Responsibilities

• Design and execute purification unit operations.
• Interact with project teams to meet goals in relation to manufacturing drug substance and technology transfer.
• Operate downstream purification equipment such as chromatography and tangential flow filtration skids.
• Maintain adequate levels of supplies and consumables.
• Perform routine safety inspections of equipment and lab areas.
• Create standard operating procedures, batch records and technical reports.
• Support evaluation of new purification technologies.
• Ensure equipment readiness through scheduling and coordination of PM and calibration activities.

Benefits

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
• Help improve the lives of millions of people globally by making drug development quicker and more effective.
• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level