Associate Scientist II, Protein Sciences

Alnylam Pharmaceuticals • Cambridge, MA

6d • Onsite

About The Position

We are seeking an associate scientist-II to join our protein sciences team to contribute to our protein production and conjugation efforts. The candidate must be independent, goal oriented, technically competent, and able to efficiently work across multiple projects. We are searching for enthusiastic, innovative, and highly motivated individuals, with scientific background in protein expression, purification, and analytical techniques, who are comfortable working in a fast-paced entrepreneurial environment. The successful candidate will be part of cross-functional teams including biologists, chemists, and pharmacologists and will contribute to advancing research programs across multiple therapeutic modalities
This lab-based position is onsite and will be located at 675 W. Kendall St. Cambridge, MA 02142

Requirements

• BS/MS degree in biology, biochemistry, biophysics, chemistry, or a related field, with 0–1 years of relevant laboratory experience in a biopharma or academic setting.
• Familiarity with protein and/or antibody structure and function.
• Detail-oriented, self-motivated, and comfortable working on highly technical projects in a multidisciplinary team setting.
• Effective written and oral communication skills.

Nice To Haves

• Experience with protein binding techniches (ELISA, flow cytometry, SPR and/or BLI) preferred.
• Experience with instrumentation such as Octet, Biacore, flow cytometers, and UV–Vis spectrometeters preferred.
• Experience with protein and protein conjugate analysis (e.g., affinity chromatography, SEC, IEX, SDS-PAGE, UV–Vis spectroscopy) preferred.
• Experience with sterile technique and/or handling mammalian cell culture is a plus.
• Passion for driving projects from the bench, independently contributing to research goals, and solving challenging problems.

Responsibilities

• Work closely with the protein sciences team to engineer and validate binding of antibodies and antibody conjugates at various production scales.
• Design, plan, and perform protein binding experiments to support in vitro and in vivo evaluations, contributing to project-related scientific activities with some guidance from team members.
• Utilize UV–Vis spectroscopy and HPLC to analyze, quantify, characterize, and formulate protein conjugates.
• Contribute to the maintenance of laboratory infrastructure and equipment.
• Support group organization, productivity, and expertise through collaboration and idea exchange.
• Meet quality, quantity, and timeline expectations for all assigned projects.
• Support discovery efforts in protein sciences.
• Maintain accurate and complete electronic notebook records.
• Communicate experimental plans and data to multiple cross-functional scientific teams.

Benefits

• We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match.
• Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks.
• We also offer generous family resources and leave.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level