Scientist II, Protein Science

ModeX Therapeutics • Weston, MA

7h

About The Position

We are seeking an experienced and highly motivated analytical biochemist to join
our Protein Science group. The individual will be a key member of the protein
analytics team tasked with analytical and functional characterization efforts
for our therapeutic programs. This role requires strong technical expertise,
scientific independence, and the ability to translate complex data into clear
conclusions that guide therapeutic lead selection and optimization.

This is an exciting opportunity to be part of a cross-functional team and
contribute to the development of cutting-edge biotherapeutics in a fast-paced,
rapidly growing biotech company with a bold vision.

Requirements

• Advanced degree required: MS or Ph.D in protein science, biochemistry, analytical chemistry or other related disciplines
• Lab experience required: MS with 10+ years or PhD with 3+ years of relevant lab or industrial experience
• Strong theoretical knowledge and hands-on experience in characterizing protein-protein interactions using SPR, BLI and ELISA to assess affinity, kinetics, and potency.
• Proficiency with protein analytics platforms such as HPLC, UPLC, DLS/SLS, and related biophysical methods for protein purity and stability assessment.
• Solid understanding of antibody structure, function, and biologics drug discovery and development workflows.
• Demonstrated ability to work independently and lead projects with minimal supervision. Attention to details, outstanding troubleshooting and problem-solving skills.
• Excellent written and oral communication, organization, and data interpretation skills.
• Highly adaptable to a fast-paced work environment and capable of working both independently and collaboratively within project teams.

Responsibilities

• Lead the in vitro functional screening and analytical characterization of multispecific antibodies and therapeutic proteins to support therapeutic lead identification and optimization.
• Independently develop and optimize high throughput protein analytics methods and contribute to our antibody developability screening platforms for the generation of robust, decision-enabling data.
• Serve as a subject matter expert in antibody binding characterization and potency analysis to assess and optimize drug candidate’s biochemical/ biophysical properties.
• Drive experimental strategy, execution, troubleshooting, data analysis, and communication with cross-functional teams.
• Ensure effective, high-quality and timely documentation in electronic laboratory notebooks.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree