Associate Scientist, Formulation Development

Regeneron Pharmaceuticals • Tarrytown, NY

28d • Onsite

About The Position

Regeneron's Formulation Development Group is seeking an Associate Scientist to support all stages of pre-clinical, clinical, commercial formulation, and drug product development for various drug product modalities. In this role, you will apply biochemical and biophysical methods to carry out developability assessment and formulation development studies on monoclonal antibody-based therapeutics, to support drug substance and drug product development.

Requirements

• B.S or MS degree in Pharmaceutical Sciences, Chemistry, Biochemistry, Biophysics, Biomedical Engineering, Analytical Chemistry, Chemical Engineering, or a related discipline with hands-on laboratory experience.
• The ability to design and execute experiments, as well as interpret, document, and communicate results with minimal supervision is required.

Nice To Haves

• Relevant industry or intern experience is preferred.
• Strong technical knowledge base and relevant experience with protein/peptide chemistry, biophysical/biochemical characterization of proteins, bioanalytical method development and biomolecule product development is desirable.
• Hands-on experience with biochemical and biophysical techniques for protein characterization, including chromatography (SEC, IEX, RP), viscosity, gel electrophoresis (CE-SDS, MCE, cIEF, iCE), particle size (DLS, HIAC, MFI), spectroscopy (UV-Vis, CD, AUC, fluorescence), and thermostability characterization (DSC, DSF) is desirable.

Responsibilities

• Design and execute phase-appropriate formulation development studies, such as formulation screening, stability, and compatibility studies, to support formulation and drug product development for early and late-stage development programs.
• Conduct biochemical and biophysical assessments and pre-formulation studies to support evaluation of preclinical drug candidates.
• Characterize drug product (lyophilized or liquid) formulation to support process development and manufacturing of clinical drug substances and drug products.
• Provide technical support for development, technology transfer and manufacture of drug substance and drug products and collaborate with cross-functional teams.
• Document findings and lab records in electronic laboratory notebook by following the organizational best practices and policies.
• Author protocols, technical documents for internal use and support regulatory filings.
• Participate in meetings and present study results in department meetings or cross-functional team meetings.
• Take part in the general laboratory and instrument maintenance.

Benefits

• comprehensive benefits, which vary by location
• health and wellness programs (including medical, dental, vision, life, and disability insurance)
• fitness centers
• 401(k) company match
• family support benefits
• equity awards
• annual bonuses
• paid time off
• paid leaves (e.g., military and parental leave)

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Industry: Chemical Manufacturing
• Number of Employees: 5,001-10,000 employees