Associate Director, In Vitro Pharmacology

Crinetics Pharmaceuticals•San Diego, CA

6d•$160,000 - $200,000

About The Position

Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. This is an exciting time to join Crinetics as we shape our organization into the world’s premier fully integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. Position Summary: We are looking for a driven and collaborative Associate Director with expertise in GPCR pharmacology, drug discovery, and proven leadership to join our dynamic and expanding in vitro pharmacology team.. The successful candidate will lead and oversee in vitro pharmacology activities, including support for lead optimization campaigns, mechanism-of-action studies, and new target initiatives within endocrinology.

Requirements

Ph.D. in Pharmacology, Biochemistry, Biology, or related discipline with a minimum of 8 years of relevant experience. Applicants with BS or MS degrees must demonstrate a minimum of 10 years of significant and relevant experience.
At least 7 years of experience with drug discovery and small molecule pharmacology at therapeutically relevant GPCRs or related field.
Minimum supervisory experience of 7 years.
Demonstrated extensive and in-depth technical proficiency in biochemical, cellular, and/or radioligand binding assay systems and ability to ensure highest quality of in vitro assay data.
Ability to independently determine in vitro pharmacologic methods and procedures to achieve Program goals.
Outstanding experimental design, problem-solving, and data analysis skills and the ability to independently establish in vitro pharmacologic approaches to achieve program goals.
Demonstrated practical experience and deep understanding of in vitro pharmacological theory, models, mechanisms, and experimental design, particularly with GPCRs
Must be independent and able to follow pre-established experimental designs, as well as develop new methods, protocols, and technologies based on existing literature.
Strong work ethic and enthusiasm for a mix of laboratory work and management in a dynamic environment.
Experience in management and daily supervision of scientific staff
Experience in program management/leadership
Strong written and verbal communication skills and ability to work effectively in a multidisciplinary team environment.
Experience with writing reports and technical regulatory documents
Must be detail-oriented, punctual, and reliable.
Ability to work in a fast-paced environment and adapt to change.

Responsibilities

Possess scientific leadership and hands-on management of a team of scientists in an environment that promotes collaboration, teamwork, and innovative science
Design, development, validation, and execution of in vitro assays that support drug discovery programs
Perform organizational management to deliver critical in vitro experimental data that supports multiple programs simultaneously
Possess high-level initiative to oversee, troubleshoot, and accurately perform data analysis in an environment that values scientific integrity and quality.
Demonstrate functional representation and lead cross-functional Program Teams
Interpret effective written and oral communication of results to interdisciplinary teams
Participate in strategic planning of departmental growth, organization, and evaluation of new targets.
Prepare technical reports to support program reviews, publications, and IND submissions
Identify and evaluate new research targets within therapeutic areas of interest.
Responsible for ensuring compliance with company established practices and procedures, including laboratory notebooks, computer files, quality and regulatory guidelines, and safety standards
Other duties as assigned.

Benefits

In addition to your base pay, our total rewards program consists of a discretionary annual target bonus, stock options, ESPP, and 401k match.
We also provide top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance, 20 days of PTO, 10 paid holidays, and a winter company shutdown.

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