Associate Director, Clinical Supply Chain

Rapport Therapeutics•Boston, MA

3d•$180,000 - $200,000•Hybrid

About The Position

When our people share why they joined Rapport and love it here, it comes down to three things: the science, the mission, and the team. At Rapport, we’re driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we’re doing this with extraordinary science and awesome people (affectionately called Rapptors). Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials for neuropathic pain and bipolar disorder. The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you’re as excited about this opportunity as we are! Your Impact: You’ll own the day-to-day global clinical supply planning and execution for assigned studies, coordinating vendors and partnering cross-functionally to ensure a steady, uninterrupted supply of investigational and future commercial materials. This role is perfect for someone who thrives in execution, is comfortable owning complex study-level operations, and enjoys collaborating closely with CMC, Clinical Operations, Quality, and Regulatory teams.

Requirements

8–12 years of progressive experience in global supply chain or clinical supply chain management within the biopharmaceutical industry.
Bachelor’s degree in Life Sciences, Engineering, Supply Chain, or related field; advanced degree preferred.
Hands-on experience supporting late-stage (Phase 2/3) clinical trials and NDA-enabling studies, and contributing to commercial readiness activities.
Solid understanding of clinical development processes, GMP/GDP requirements, and global regulatory expectations for small molecule therapeutics.
Experience managing external manufacturing, packaging, labeling, and logistics partners.
Demonstrated ability to manage complex operational details while maintaining a strategic perspective.
Strong communication, problem-solving, and cross-functional collaboration skills.

Nice To Haves

ASCM/APICS certification preferred (e.g. CSCP, CPIM)

Responsibilities

Lead global clinical supply planning and execution to support Phase 3 trials, including demand forecasting, inventory strategy, production planning, and distribution.
Ensure timely, compliant supply of drug substance, drug product, and clinical trial materials to global clinical sites.
Partner closely with CMC, Clinical Operations, Regulatory, Quality, and Program Management to align supply plans with manufacturing campaigns, clinical timelines, and regulatory milestones.
Support supply chain readiness for pivotal trials, regulatory submissions, and early commercial planning.
Manage day-to-day relationships with CDMOs, packaging and labeling vendors, and logistics providers.
Support contract execution, performance monitoring, issue resolution, and continuous improvement initiatives across external partners.
Own clinical demand forecasting, inventory visibility, and supply reconciliation processes.
Leverage supply chain systems, planning tools, and dashboards to enable data-driven decision-making and scenario planning.
Identify supply chain risks related to capacity, lead times, regulatory requirements, or geopolitical factors and develop mitigation plans in partnership with leadership.
Contribute to the development and refinement of SOPs, KPIs, and scalable processes to support company growth.
Provide functional leadership within supply chain initiatives and project teams.
Contribute to establishing a culture of accountability, innovation, and continuous improvement aligned with company values and growth objectives.