2026 Summer Intern - BioAnalytical Sciences

Roche • South San Francisco, CA

6d • $40 - $46 • Onsite

About The Position

Our BioAnalytical Sciences Department is a world-class bioanalytical center of excellence for novel strategies, technologies, and methods that enable the development of life-changing medicines. We do this by fostering an innovative and collaborative environment that values and recognizes diversity of contributions. We are seeking a highly-motivated intern to join our team for the summer of 2026. The successful candidate for this laboratory-based position will work closely with our scientific team to develop and explore methodologies to investigate the stability and accurate quantification of drug candidates in complex biological matrices using mass spectrometry (MS). This project is essential for ensuring the analytical robustness and data quality required for establishing the safety and efficacy of novel therapeutics during early drug development. The project will utilize state-of-the-art sample processing methodologies and advanced preparation techniques paired with the latest techniques in MS. The ideal candidate will have strong general laboratory skills, including excellent wet-laboratory technique, attention to detail in sample preparation and mixing, the ability to perform rapid and accurate calculations, and familiarity with common laboratory consumables. They should also have a general understanding of liquid chromatography (LC), tandem MS, and protein/peptide analysis methods. This internship position is located in South San Francisco, on-site. The Opportunity The intern will focus on hands-on method development for LC-MS–based assays to evaluate drug candidate integrity and quantify analytes across a range of biological matrices. They will receive training and gain practical experience operating targeted mass spectrometry platforms, with an emphasis on Triple Quadrupole MS systems. The intern will learn and perform tissue sample processing and handling techniques essential for bioanalytical studies. They will design and execute optimization experiments involving novel sample-processing strategies and advanced buffer chemistries to ensure sample integrity and analytical robustness. The intern will conduct high-sensitivity LC-MS analysis and perform extensive data processing to quantify analytes, assess assay performance, and support workflow improvements. Throughout the internship, the intern will provide regular written and oral updates on their progress. At the end of the program, they will deliver a comprehensive summary of their work—presenting a poster at the Genentech intern poster session and sharing their findings in presentations to the BAS group and its leadership team. Program Highlights Intensive 12-weeks, full-time (40 hours per week) paid internship. Program start dates are in May/June 2026. A stipend, based on location, will be provided to help alleviate costs associated with the internship. Ownership of challenging and impactful business-critical projects. Work with some of the most talented people in the biotechnology industry.

Requirements

• Must be pursuing a Master's Degree (enrolled student).
• Must be pursuing a PhD (enrolled student).
• Analytical Chemistry, Biochemistry, Chemical Engineering, Biology or related discipline.
• Some mass spectrometry experience, including a general understanding of liquid chromatography, tandem mass spectrometry, and protein/peptide analysis workflows, is essential.
• Strong laboratory experience is required; hands-on work with biological sample-processing methods—such as tissue handling and processing—is desirable, though these skills will also be developed through internship training.
• High level of self-motivation, with the ability to work independently, take initiative, and proactively troubleshoot or seek guidance when needed.

Nice To Haves

• Excellent communication, collaboration, and interpersonal skills, along with a strong willingness and curiosity to learn.
• Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

Responsibilities

• Hands-on method development for LC-MS–based assays to evaluate drug candidate integrity and quantify analytes across a range of biological matrices.
• Receive training and gain practical experience operating targeted mass spectrometry platforms, with an emphasis on Triple Quadrupole MS systems.
• Learn and perform tissue sample processing and handling techniques essential for bioanalytical studies.
• Design and execute optimization experiments involving novel sample-processing strategies and advanced buffer chemistries to ensure sample integrity and analytical robustness.
• Conduct high-sensitivity LC-MS analysis and perform extensive data processing to quantify analytes, assess assay performance, and support workflow improvements.
• Provide regular written and oral updates on their progress.
• Deliver a comprehensive summary of their work—presenting a poster at the Genentech intern poster session and sharing their findings in presentations to the BAS group and its leadership team.

Benefits

• Intensive 12-weeks, full-time (40 hours per week) paid internship.
• Program start dates are in May/June 2026.
• A stipend, based on location, will be provided to help alleviate costs associated with the internship.
• Ownership of challenging and impactful business-critical projects.
• Work with some of the most talented people in the biotechnology industry.
• paid holiday time off benefits

What This Job Offers

• Job Type: Full-time
• Career Level: Intern
• Number of Employees: 5,001-10,000 employees