2026 Summer Intern – Bioanalytical Sciences
About The Position
2026 Summer Intern – Bioanalytical Sciences Department Summary We are seeking a highly motivated student to join the BioAnalytical Sciences (BAS) department within Development Sciences for a summer internship. The BioAnalytical Sciences Department at Genentech is a world-class bioanalytical center of excellence for novel strategies, technologies, and methods that enable the development of life-changing medicines. We do this by fostering an innovative and collaborative environment that values and recognizes diversity of contributions. The Cell Biology division focuses on investigating the mechanism of action of biotherapeutics through cell-based assays such as cellular internalization and processing, high content imaging, and real-time cell growth/survival monitoring. Your work will consist in the development of cell-based assays and will utilize cell culture, flow cytometry, and other immunology related methods. This internship position is located in South San Francisco, on-site. The Opportunity Project background: Chimeric antigen receptor T (CAR-T) cells are engineered T cells with promising potential to provide curative treatment for hematologic malignancies. However, due to the highly personalized manufacturing process and extremely high treatment cost, only ~20% of eligible patients currently have access to autologous CAR-T therapies. Allogeneic CAR-T cell products offer an “off-the-shelf” alternative that has the potential to improve treatment accessibility. However, most current allogeneic CAR-T therapies exhibit limited persistence in patients and therefore do not achieve the durable responses observed with autologous CAR-T cells. This reduced persistence is likely due to immunologic rejection of the allogeneic CAR-T cells by the host immune system. Therefore, understanding the mechanisms of host immune rejection is essential to guide the development of next-generation allogeneic CAR-T cell designs that can evade immune clearance and achieve durable persistence in patients.
Requirements
- Must be pursuing a Bachelor’s degree (enrolled student); completion of at least three years of coursework is preferred.
- Must be pursuing a Master's Degree (enrolled student).
- Must be pursuing a PhD (enrolled student).
- Required Majors: Immunology, Biology or Pharmacology related fields.
Nice To Haves
- Excellent communication, collaboration, and interpersonal skills.
- Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.
- Immunology related skills. E.g: FACS, Immune cell isolations (PBMC, Tcells, Nkcells), cell-based assays, primary blood cell culturing, ELISPOT, Luminex, ELISA.
Responsibilities
- Determine whether T cell–depleted patient-derived PBMCs can still mediate CAR-T cell killing.
- Determine whether NK cell–depleted patient-derived PBMCs can still mediate CAR-T cell killing.
- Quantify the CAR-T cell killing activity of T cell– and NK cell–depleted PBMCs compared with undepleted PBMCs.
Benefits
- Intensive 12-weeks, full-time (40 hours per week) paid internship.
- Program start dates are in May/June 2026.
- A stipend, based on location, will be provided to help alleviate costs associated with the internship.
- Ownership of challenging and impactful business-critical projects.
- Work with some of the most talented people in the biotechnology industry.
- Final presentations of project work to senior leaders.
- Professional & personal development curriculum throughout the program, including networking opportunities, workshops, and panel discussions.
- Participate in volunteer projects, social events, and team-building activities.
- paid holiday time off benefits
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What This Job Offers
Job Type
Full-time
Career Level
Intern
Number of Employees
5,001-10,000 employees
