Translational Research Scientist, Oncology

BillionToOne•Menlo Park, CA

3h•$126,721 - $147,841•Onsite

About The Position

Ready to redefine what's possible in molecular diagnostics? Join a team of brilliant, passionate innovators who wake up every day determined to transform healthcare. At BillionToOne, we've built something extraordinary—a culture where transparency fuels trust, collaboration drives breakthroughs, and every voice matters in our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we strive to build products that are 10x better than anything that exists today. Our people are our greatest asset: talented scientists, engineers, sales professionals, and visionaries united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion—every innovation you contribute helps remove fear of unknown from some of life's most critical medical moments. If you're driven by purpose, energized by innovation, and ready to help build the future of precision medicine, this is where you belong. We are looking for a Translational Research Scientist, Oncology to join a fast-growing team. This person will be responsible for bridging the gap between our cutting-edge molecular assays and clinical outcomes. You will own the analysis of clinical data, develop sophisticated statistical models to validate our Northstar oncology products, and play a pivotal role in the design and execution of clinical studies. The Translational Research Scientist role is a full-time onsite position and reports to the Associate Director of Oncology Translational Research.

Requirements

PhD in Biostatistics, Bioinformatics, Cancer Biology, Epidemiology, or a related quantitative field.
2+ years of experience working with clinical datasets and conducting survival analysis (specifically Cox PH and time-to-event modeling).
Proven track record of analyzing and cleaning large-scale clinical data from trials or electronic health records (EHR).
Fluency in Python or R for statistical computing and data visualization.
Deep understanding of oncology and the clinical applications of NGS-based diagnostics.
Excellent communication and presentation skills, with the ability to explain complex statistical concepts to non-experts.

Nice To Haves

Experience in a fast-paced start-up environment.
Experience working in a regulated environment (MolDX or FDA-regulated study designs).
Familiarity with clinical data standards (e.g., CDISC/SDTM).
Experience with SQL and cloud-based data environments (S3/AWS/GCP).

Responsibilities

Clinical Data Orchestration: Lead the cleaning, preprocessing, and integration of complex clinical datasets with molecular informatics to ensure high-quality inputs for downstream analysis.
Statistical Modeling: Develop and implement robust clinical-statistical models, including Cox Proportional Hazards (Cox PH), Kaplan-Meier estimates, and logistic regression, to evaluate clinical utility and patient outcomes.
Clinical Study Support: Provide data-informed recommendations for the design and analysis of clinical studies, ensuring protocols are optimized to demonstrate the validity of our oncology assays.
Insights Generation: Analyze assay performance within clinical cohorts and contribute to high-impact publications and regulatory submissions that establish the standard of care.
Cross-Functional Collaboration: Partner with R&D scientists to translate laboratory breakthroughs into clinical insights and collaborate with clinical trial operations to monitor study progress. Partner with numerous internal and external teams to drive scientific results
Communication: Present complex statistical findings and clinical insights to internal stakeholders, clinical investigators, and at scientific conferences.

Benefits

Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
Open, transparent culture that includes weekly Town Hall meetings
The ability to indirectly or directly change the lives of hundreds of thousands patients
Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
Supplemental fertility benefits coverage
Retirement savings program including a 4% Company match
Increase paid time off with increased tenure
Latest and greatest hardware (laptop, lab equipment, facilities)
Daily on-site lunches provided from top eateries
A variety of perks on campus (state of the art gym, restaurant)
Free on-site EV charging (compatible with all EVs, including Tesla)
At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).
For this position, we offer a total compensation package of $202,625 per year, including a base pay range of $126,721 - $147,841 per year.