Picarro, Inc-posted 11 days ago
Full-time • Mid Level
Santa Clara, CA
101-250 employees

We seek a Systems Engineer with a strong background in analytical instrumentation and experimental system design. The ideal candidate combines hands-on hardware proficiency with experience in Python programming, quantitative analysis of data, and infrared spectroscopy. You will play a key role in developing and integrating advanced measurement systems that combine novel sample handling with laser-based and spectroscopic analytical technologies.

  • Design, develop, and test advanced analytical and spectroscopic systems that meet strategic technical and commercial goals
  • Plan and execute experiments to evaluate system performance, signal stability, and detection limits, using principles of experimental design and statistical analysis
  • Develop algorithms and analytical software in Python to process, interpret, and visualize spectroscopic data
  • Create and test new system architectures integrating optical, electrical, mechanical, and software subsystems.
  • Formulate manufacturing specifications and test protocols to ensure reliable, scalable production of prototype and commercial systems.
  • Lead and maintain technical documentation—including product specifications, design history files, validation plans, system requirements, and NPI process documentation.
  • Collaborate with scientists and engineers across optical design, chemistry, electronics, mechanical design, and software to optimize system performance
  • Conduct data-driven performance analyses and support algorithmic improvements to enhance sensitivity, selectivity, and real-time response
  • Lead risk management and design reviews (failure mode and effects analysis, fault tree analysis, etc.) to ensure system robustness and regulatory compliance
  • M.S. or Ph.D. in Engineering, Physics, Applied Physics, Physical Chemistry, or a related field
  • Proven experience with analytical or spectroscopic instrumentation
  • Demonstrated ability to design and execute experiments, interpret results quantitatively, and refine system parameters based on data
  • Proficiency in Python for scientific computation, data processing, and algorithm development (e.g., NumPy, SciPy, pandas, matplotlib)
  • Understanding of infrared spectroscopy, including molecular structure–spectrum relationships.
  • Experience with system-level integration across optical, mechanical, and electronic subsystems.
  • Excellent documentation, communication, and project management skills
  • Familiarity with data modeling, signal processing, or machine learning approaches for instrument data analysis is a plus
  • Experience developing industrial or laboratory analytical instruments from concept through production
  • Familiarity with ISO/IEC-compliant design and validation processes
  • Extensive hands-on proficiency with spectroscopic or laser-based instrumentation
  • Experience with pneumatic control systems or components
  • Knowledge of real-time data acquisition systems and hardware–software interfacing.
  • Background in Design of Experiments (DoE) and reliability testing.
  • General ability with hand tools and equipment. Experience building or testing gas or liquid handling systems a plus.
  • Medical, Dental, and Vision insurance
  • Flexible Spending Account (FSA) and Health Savings Account (HSA) plans
  • Life, Short-Term Disability, and Long-Term Disability Insurance
  • Paid Time Off and Paid Holidays
  • Employee Referral Program
  • 401K
  • Social events (summer picnic, holiday party, team lunches, etc.)
  • On-site Health & Wellness programs (fitness challenges, outdoor bootcamp, flu-shots, etc.)
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