Staff Scientist

University of Chicago • Hyde Park, IL

19h • Onsite

About The Position

The principal contribution of a Staff Scientist is leading translational research projects under mentorship of Dr. Chuan He in the Department of Chemistry. The He Lab group is looking for a highly experienced molecular biologist who has previous research experience in developing sequencing method for RNA and DNA modifications, and in DNA/RNA methylation and gene expression regulation. The Staff Scientist will work on research projects involving DNA/RNA modification profiling, high-throughput sequencing-based assays, new genomic method development, perform molecular biology experiments and coordinate lab research. The candidate needs to have a Ph.D. Degree in molecular biology and previous postdoc experience in molecular biology.

Requirements

• Minimum requirements include a PhD in related field.
• Minimum requirements include knowledge and skills developed through < 2 years of work experience in a related job discipline.
• CV (required)
• References (preferred)

Nice To Haves

• PhD in Biology, Molecular Biology, or related field.
• Postdoc experience in molecular biology.
• Knowledge of basic computer proficiency including computer programs and standard laboratory equipment.
• Knowledge of relevant scientific fields.
• Knowledge of regulatory policies and procedures.
• Demonstrated problem-solving, organization, analytical, and coordination skills including attention to detail.
• Demonstrated excellent oral and written communication skills.
• Demonstrated ability to read and comprehend scientific and technical literature, and methods to stay abreast of developments in the field.
• Ability to work independently and as a part of a team and interact with a diverse workforce.
• Ability to think creatively.
• Demonstrated ability to articulate their scientific discoveries both in written publications and in talks.

Responsibilities

• Perform routine and advanced molecular biology experiments, including nucleic acid extraction, purification, quantification, PCR/RT-PCR, and gel-based analysis.
• Prepare and process RNA and DNA samples for next-generation sequencing (NGS) workflows, including library preparation and QC steps.
• Support large-scale projects aimed at profiling DNA/RNA modification patterns across biological samples.
• Manage the development, optimization, and evaluation of new genomic and epitranscriptomic methods, including experimental troubleshooting and protocol refinement.
• Operates in a highly collaborative mode with all members of the group and with others in the Institute and with off-campus collaborators.
• Under general supervision of principal investigator, supervise and/or assist with the complex technical duties in a laboratory doing non-clinical research.
• Compile documents and assists with interpreting presentations or reports stemming from scientific contributions in the laboratory.
• Gives frequent internal and occasional external talks and tutorials on the thinking and work progress.
• Leads the contributions to scientific writing and publications, including protocols and grants.
• Mentor and supervise lab technician and undergraduate students within the group.
• Performs experiments and collects and analyzes data.
• Participates in the promotion of a research project.
• May present work at scientific meetings.
• Performs other related work as needed.

Benefits

• The University of Chicago offers a wide range of benefits programs and resources for eligible employees, including health, retirement, and paid time off.
• Information about the benefit offerings can be found in the Benefits Guidebook .

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees