Sr Staff Clinical Program Manager

Dexcom

3d • $135,100 - $225,100 • Remote

About The Position

The Company Dexcom Corporation (NASDAQ DXCM) is a pioneer and global leader in continuous glucose monitoring (CGM). Dexcom began as a small company with a big dream: To forever change how diabetes is managed. To unlock information and insights that drive better health outcomes. Here we are 25 years later, having pioneered an industry. And we're just getting started. We are broadening our vision beyond diabetes to empower people to take control of health. That means personalized, actionable insights aimed at solving important health challenges. To continue what we've started: Improving human health. We are driven by thousands of ambitious, passionate people worldwide who are willing to fight like warriors to earn the trust of our customers by listening, serving with integrity, thinking big, and being dependable. We've already changed millions of lives and we're ready to change millions more. Our future ambition is to become a leading consumer health technology company while continuing to develop solutions for serious health conditions. We'll get there by constantly reinventing unique biosensing-technology experiences. Though we've come a long way from our small company days, our dreams are bigger than ever. The opportunity to improve health on a global scale stands before us. Meet the team: Our Global Clinical Program Management team leads Dexcom's worldwide clinical portfolio with a focus on strategic execution, scientific rigor, and seamless collaboration across functions and regions. We design and deliver complex, multi‑region clinical programs that not only navigate diverse regulatory pathways but also generate the robust evidence needed to support market access, reimbursement, and adoption across North America, Europe, APAC, LATAM, and emerging markets. As a key member of this organization, the Sr. Staff Clinical Program Manager helps translate product strategy into actionable global clinical plans—guiding cross‑functional teams through study design, site and country strategy, execution, and ongoing evidence generation. This role thrives in a fast‑paced, international environment and contributes to a culture built on innovation, operational excellence, and the development of high‑performing, globally fluent clinical leaders. Where you come in: Serve as the clinical program leader for one or more global, cross‑functional core teams—translating product strategy into executable clinical program plans and ensuring alignment with broader technical, regulatory, and business objectives. Define and drive the clinical program roadmap, including strategy, requirements, milestones, and interdependencies across multiple complex studies. Lead global study teams through all phases of execution—from early design and feasibility through study close‑out—ensuring scientific rigor, operational excellence, and compliance with worldwide Good Clinical Practice (GCP), ISO 14155, and other regional regulatory requirements. Interface at a senior level with Executive Management, R&D, Regulatory Affairs, Quality, Operations, Marketing, and external partners/CROs to ensure technical and operational integration across program components. Operationalize global clinical strategies, including study design approaches, regulatory evidence pathways, and site/country selection strategies informed by regional regulatory landscapes. Oversee and manage complex program budgets, financial forecasting, and global resource allocation, ensuring optimal use of internal/external resources. Establish and monitor KPIs for clinical execution, proactively identifying risks to study startup, enrollment, data quality, regulatory compliance, and program timelines—and driving mitigation strategies across global teams. Lead vendor strategy and governance, including CRO and specialized vendor selection, contract oversight, performance management, and escalation resolution for multi‑region programs. Implement innovative operational models and tools to optimize efficiency, quality, and scalability of global clinical execution (e.g., digital trial capabilities, centralized monitoring approaches, risk‑based quality management). Represent the clinical program externally, providing senior‑level engagement with investigators, global KOLs, regulatory bodies (as appropriate), and other external stakeholders to ensure alignment on scientific and regulatory expectations. Ensure integration of clinical insights into product development, partnering closely with R&D and technical program management teams to translate clinical outcomes into product improvements and future evidence needs.

Requirements

• You have a strong regulatory knowledge, including Good Clinical Practices (GCPs) and ISO 14155.
• You have experience with protocol, ICF, CRF development.
• You have experience with global clinical study planning and execution in the medical device industry.
• You have experience serving as a Clinical representative on a product development core team.
• You have exceptional organizational skills and ability to deal with competing priorities, also strong reasoning and problem-solving ability.
• You have excellent communication (written and verbal) and presentation skills along with leadership qualities.
• You have strong interpersonal skills and ability to work effectively on cross-functional & global teams.
• You thrive in an extremely fast-paced environment.
• Typically requires a Bachelor's degree in a technical discipline, and a minimum of 13+ years related experience or a Master's degree and 8+ years equivalent industry experience of a PhD and 5+ years of experience

Nice To Haves

• Successful experience managing outside CRO groups in Class II/III, preferably diabetes, device studies
• Proficient with MS Office Suite (Excel, Word and PowerPoint), MS Project, and Smartsheet

Responsibilities

• Serve as the clinical program leader for one or more global, cross‑functional core teams—translating product strategy into executable clinical program plans and ensuring alignment with broader technical, regulatory, and business objectives.
• Define and drive the clinical program roadmap, including strategy, requirements, milestones, and interdependencies across multiple complex studies.
• Lead global study teams through all phases of execution—from early design and feasibility through study close‑out—ensuring scientific rigor, operational excellence, and compliance with worldwide Good Clinical Practice (GCP), ISO 14155, and other regional regulatory requirements.
• Interface at a senior level with Executive Management, R&D, Regulatory Affairs, Quality, Operations, Marketing, and external partners/CROs to ensure technical and operational integration across program components.
• Operationalize global clinical strategies, including study design approaches, regulatory evidence pathways, and site/country selection strategies informed by regional regulatory landscapes.
• Oversee and manage complex program budgets, financial forecasting, and global resource allocation, ensuring optimal use of internal/external resources.
• Establish and monitor KPIs for clinical execution, proactively identifying risks to study startup, enrollment, data quality, regulatory compliance, and program timelines—and driving mitigation strategies across global teams.
• Lead vendor strategy and governance, including CRO and specialized vendor selection, contract oversight, performance management, and escalation resolution for multi‑region programs.
• Implement innovative operational models and tools to optimize efficiency, quality, and scalability of global clinical execution (e.g., digital trial capabilities, centralized monitoring approaches, risk‑based quality management).
• Represent the clinical program externally, providing senior‑level engagement with investigators, global KOLs, regulatory bodies (as appropriate), and other external stakeholders to ensure alignment on scientific and regulatory expectations.
• Ensure integration of clinical insights into product development, partnering closely with R&D and technical program management teams to translate clinical outcomes into product improvements and future evidence needs.

Benefits

• A front row seat to life changing CGM technology.
• Learn about our brave #dexcomwarriors community.
• A full and comprehensive benefits program.
• Growth opportunities on a global scale.
• Access to career development through in-house learning programs and/or qualified tuition reimbursement.
• An exciting and innovative, industry-leading organization committed to our employees, customers, and the communities we serve.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees