Sr Scientist, Biomarkers

Thermo Fisher Scientific • Cambridge, MA

4d • Onsite

About The Position

Join us as Senior Scientist! This is a fully onsite role based at our customer’s site in Cambridge, MA. We welcome applicants from all locations within the US. Please note that relocation assistance is not provided for this position, and any relocation costs will be the responsibility of the candidate. Must be legally authorized to work in the United States without sponsorship. Must be able to pass a comprehensive background check, which includes a drug screening. Thermo Fisher's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission – to enable our customers to make the world healthier, safer, and cleaner. Within our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to leverage the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits. Summarized Purpose The Exploratory Biomarkers group is seeking an enthusiastic scientist who will be involved in protein biomarker discovery and analysis with the goals of understanding disease mechanisms, human target validation and drug effect evaluation by implementing ultra-sensitive affinity-based proteomic technologies (ie, Simoa, MSD, NULISA). This scientist will also be responsible for evaluating and implementing emerging technologies/methods, including assay verification in new sample matrix, as well as maintaining operational readiness of laboratory equipment.

Requirements

• BS Degree in Biochemistry, Biotechnology or related disciplines with minimum 4-6 years of experience in protein biomarker immunoassay development and implementation or MS Degree with 2-4 years in above related experience
• In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
• In-depth knowledge of low plex and single plex immunoassays: ie, Traditional ELISA, Meso Scale Discovery (MSD), Ella.
• Comprehensive understanding of Simoa technology and workflow (Hands-on experience is highly desired)
• Thorough understanding of NULISA technology (Experience in operating and data analysis preferred)
• Experience in handling biological materials (plasma, serum, CSF, tissues, etc.).
• Lab automation (liquid handling workstations, plate washers).
• Strong organizational and record keeping skills; attention to detail and meticulousness are critical.
• Demonstrated strength in communication and professional presentations.

Responsibilities

• Conduct study sample analysis using affinity based proteomic technologies (ELISA, ELLA, Simoa, NULISA…) to support projects in immunology and neurology.
• Novel assay development, validation and implementation for immunology and neurology project using homebrew methodology (MSD, SIMOA, NULISA), including feasibility development for novel sample matrix (ie, skin tape, dry blood….)
• Maintain detailed records of experimental work by entering data in Benchling.
• Maintain all relevant lab equipment in good condition.
• Conduct independent data analysis and report results to the lab head in a timely manner.

Benefits

• A choice of national medical and dental plans, and a national vision plan, including health incentive programs
• Employee assistance and family support programs, including commuter benefits and tuition reimbursement
• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
• Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
• Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees