Sr Payroll Manager

NateraSan Carlos, CA
12h

About The Position

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

Requirements

  • Bachelor's degree in Accounting, Finance, Business, or a related field required; Master’s degree or MBA a plus.
  • Minimum of 8–10 years of progressive payroll experience, including 3+ years in a people management role.
  • Strong experience managing payroll operations in a high-growth, multi-state environment with 5,000+ employees.
  • Expertise with Workday Payroll, UltiPro (UKG Pro) or a comparable enterprise payroll platform is required; system implementation experience highly preferred.
  • Certified Payroll Professional (CPP) strongly preferred.
  • Expert-level knowledge of federal, state, and local payroll regulations, tax compliance, and reporting requirements.
  • Demonstrated ability to lead through ambiguity, drive results, and influence stakeholders across departments.
  • Strong analytical and critical thinking skills; able to diagnose complex issues and implement sustainable solutions.
  • Proven ability to manage confidential information with discretion and integrity.
  • Exceptional communication skills, with experience presenting to senior leadership and external auditors.
  • Process improvement and systems-savvy mindset, with a track record of streamlining payroll operations and leveraging technology.
  • Will be overseeing payroll team.

Responsibilities

  • Lead, coach, and develop a high-performing payroll team, ensuring accurate and timely processing of payroll for a workforce of 5,000+ employees across multiple states and business units.
  • Own the payroll strategy and roadmap, driving continuous improvement, automation, and alignment with enterprise priorities.
  • Oversee and refine internal controls, data integrity practices, and payroll compliance to mitigate risk and ensure audit readiness.
  • Serve as a strategic partner to Finance, Accounting, HR, and Legal, providing payroll insights and aligning payroll processes with business and regulatory requirements.
  • Manage vendor relationships, including third-party payroll providers, tax agencies, and system vendors, ensuring accountability and service excellence.
  • Lead or co-lead payroll system implementations, upgrades, and integrations with timekeeping, HRIS, and financial systems.
  • Ensure accurate calculation and application of complex pay components including bonuses, equity, commissions, retro pay, garnishments, and various leave types.
  • Stay up to date on evolving payroll legislation and translate regulatory changes into clear, compliant policies and workflows.
  • Develop and deliver KPIs and executive-level reporting to support strategic decision-making and resource planning.
  • Act as escalation point for complex or sensitive payroll issues requiring judgment, cross-functional coordination, or executive visibility.
  • Management of the payroll team.

Benefits

  • Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
  • Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits.
  • Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more.
  • We also offer a generous employee referral program!
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