Sr. Medical Director, Medical Affairs

BridgeBio Pharma

4h•Hybrid

About The Position

The Sr. Medical Director, Medical Affairs is a senior medical and scientific leadership role within Medical Affairs. This role is responsible for supporting the development and execution of the medical strategy for encaleret across clinical development programs, including autosomal dominant hypocalcemia type 1 (ADH1) and chronic hypoparathyroidism. The position is critical to advancing scientific engagement, evidence generation and dissemination, clinical development support, and lifecycle planning, and to preparing for United States launch and post marketing activities. The Sr. Medical Director, Medical Affairs will serve as a key cross-functional partner, providing medical expertise and strategic leadership and partnership across Clinical Development, Regulatory, Commercial, Patient Advocacy, and Field Medical. This role will also represent BridgeBio externally with investigators, key opinion leaders (KOLs), patient organizations, and the broader scientific community.

Requirements

MD, DO, PharmD, PhD, or equivalent advanced scientific or clinical degree
7+ years of experience in Medical Affairs, Clinical Development, or related roles within the biopharmaceutical industry and/or academic medicine
Strong scientific and clinical acumen with the ability to translate complex data into clear medical insights
Proven leadership and influence in cross-functional, matrixed environments
Excellent written and verbal communication skills
Strong understanding of regulatory and compliance requirements impacting Medical Affairs and field activities
Ability to work independently in a fast-paced, evolving organization
Strategic mindset with hands-on execution capability

Nice To Haves

Deep experience in endocrinology, rare diseases, or metabolic disorders strongly preferred
Demonstrated experience supporting late-stage development, launch preparation, and post-marketing medical activities

Responsibilities

Support development and execution of the United States Medical Affairs strategy for encaleret in ADH1 and chronic hypoparathyroidism, and support Medical Affairs launch readiness and lifecycle planning, serving as an internal medical expert with scientific rigor and patient focused decision making
Lead integrated evidence generation planning and manage execution, including real world evidence generation, Phase 4 studies, registries, investigator initiated research support, and data integration activities
Lead an omnichannel Health Care Professional engagement strategy, integrating field and digital scientific exchange to gather insights and inform internal Medical Affairs programs
Build and sustain strategic relationships with key opinion leaders, investigators, and external stakeholders across endocrinology, nephrology, and related specialties, and lead advisory board and expert panel planning and execution
Partner with Clinical Development to support ongoing and planned clinical trials and contribute to scientific data disclosure and publication strategy development in collaboration with Scientific Communications
Provide medical leadership for peer to peer scientific exchange and external education programs, including scientific presentations and representation at scientific congresses, clinical meetings, and external forums
Serve as medical reviewer and approver for medical, commercial, and patient advocacy materials, and support patient finding initiatives and Field Medical strategy and training in partnership with cross functional stakeholders, ensuring compliance with applicable regulations and internal Medical Affairs policies

Benefits

Market leading compensation
401K with 100% employer match on first 3% & 50% on the next 2%
Employee stock purchase program
Pre-tax commuter benefits
Referral program with $2,500 award for hired referrals
Comprehensive health care with 100% premiums covered - no cost to you and dependents
Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions)
Hybrid work model - employees have the autonomy in where and how they do their work
Unlimited flexible paid time off - take the time that you need
Paid parental leave - 4 months for birthing parents & 2 months for non-birthing parents
Flex spending accounts & company-provided group term life & disability
Subsidized lunch via Forkable on days worked from our office
People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility
We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, Spring Health & BetterUp Coaching
We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities