Director, Medical Affairs

PepGen•Boston, MA

2d•$183,000 - $274,000

About The Position

PepGen is hiring a Director, Medical Affairs to lead the development and execution of the company’s global medical affairs strategy. This role will play a critical leadership position within Medical Affairs and will have close crossover with Patient Advocacy, Clinical Development, Regulatory, and Corporate Communications. Reporting to the Vice President, Clinical Science, this individual will be responsible for building and operationalizing an expanding Medical Affairs capability, ensuring high levels of scientific rigor, compliance, and alignment with corporate objectives. The ideal candidate brings a strong scientific background, deep experience in Medical Affairs and a proven track record of building Medical Affairs programs in a clinical-stage biotech environment.

Requirements

Advanced degree in a scientific discipline; strong foundational scientific and clinical knowledge required.
8+ years of experience in Medical Affairs, Medical Communications, Clinical Development or Scientific Publications within biotech or pharmaceutical organizations.
Demonstrated experience building or significantly expanding a Medical Affairs function or program, particularly in a clinical-stage company.
Proven expertise in publication strategy and execution, including congress planning and peer-reviewed manuscript development.
Excellent written and verbal communication skills, with the ability to translate complex scientific data for diverse scientific and patient-focused audiences.
Strong working knowledge of global publication standards and compliance requirements (e.g., ICMJE, GPP, FDA, EMA).
Experience collaborating cross-functionally with Clinical Development, Regulatory, Patient Advocacy, Legal, and Corporate Communications.
Experience supporting publications across multiple phases of development, with ability to adapt strategy as programs mature.
Demonstrated ability to lead multiple projects, set priorities, and work independently in a fast-paced biotech environment.

Responsibilities

Develop and lead the Global Medical Affairs function at PepGen, including developing the strategy for external data dissemination across clinical and scientific audiences and engagement with key opinion leaders.
Oversee development of abstracts, posters, podium presentations, manuscripts, plain-language summaries, and other scientific materials for conferences, medical congresses and peer-reviewed journals with input from internal and external KOLs.
Work closely with internal team members to facilitate and support congress strategy at scientific meetings, including KOL engagement planning, insight gathering on key topics, and developing interpretive reports to share with cross functional teams.
Work closely with internal team members to facilitate and support clinical and scientific advisory board meetings.
Prepare presentations and present to external audiences, including at conferences, advisory boards and medical education events.
Serve as a key Medical Affairs partner to Clinical Operations, Clinical Development and Clinical Science to translate complex data into clear, accurate, and impactful scientific narratives.
Collaborate with Clinical Development, Corporate Communications, and Patient Advocacy to ensure consistent scientific messaging across internal and external channels while maintaining appropriate separation of promotional and non-promotional activities.
Establish and maintain highly credible scientific relationships with academic and medical thought leaders.
Partner closely with Patient Advocacy to ensure publications and scientific communications incorporate patient-relevant outcomes, disease burden, and patient perspectives where appropriate and compliant.
Build and operationalize an evolving Medical Affairs program, including governance, processes, standards, and cross-functional ways of working.
Ensure all publication activities adhere to global regulatory, legal, and compliance requirements, including ICMJE, GPP, FDA, EMA, and internal SOPs.
Maintain awareness of competitor publications, congress activity, and evolving standards in scientific communication within relevant therapeutic areas.