Sr Engineer I, Manufacturing Sciences (Cell Culture)

Biogen • Research Triangle Park, NC

2d

About The Position

About This Role The Senior Engineer I, Manufacturing Sciences Cell Culture will contribute as a scientific resource on cell culture bioprocessing for drug substances manufactured at Biogen’s RTP facility. This role enables successful production of biopharmaceuticals by designing and performing cell culture experiments in the laboratory, leading process transfer activities for upstream GMP operations, and providing scientific support to ongoing manufacturing campaigns. What You’ll Do Provide in-depth technical expertise on cell growth and bioreactor culture for biologics drug substance production, in support of technology transfer to manufacturing and process improvement activities. Proactively identify opportunities to generate experimental data for improving process robustness, increased process understanding, and/or troubleshooting issues. Lead cross-functional project teams, collaborate with technical development, and support engineering and GMP batch production. Own laboratory studies including experimental design, planning, execution, and documentation. Support investigations as the technical SME as needed. Prevent process deviation recurrences through implementation of proper corrective measures. Represent the technical manufacturing process perspective on items such as change control, continuous improvement, capital projects, and new component introduction. Support Process Validation batch production activities and assure smooth transition of process to commercial operations. Develop technical conclusion reports summarizing process validation activities. Effectively and efficiently communicate analysis of manufacturing data and experimental results to key stakeholders. Author technical reports as needed. Who You Are You are a highly motivated and creative individual with applicable knowledge in mammalian cell culture for drug substance manufacture. You enjoy hands-on laboratory techniques, analyzing complex information, developing solutions to improve operations, and collaborating in diverse teams.

Requirements

• Bachelors degree in Engineering or relevant scientific/technical discipline with 4+ years of relevant experience OR Masters degree in Engineering or relevant scientific/technical discipline with at minimum 2+ years of direct experience OR Ph.D. in Engineering or relevant scientific/technical discipline.
• Technical knowledge of biopharmaceutical manufacturing.
• Ability to analyze scientific data sets, generate hypotheses, design experiments, and manage execution of cell culture laboratory studies.
• Excellent communication skills; ease and comfort in interacting with various teams in identifying solutions to support manufacturing activities.

Nice To Haves

• Cell Culture experience preferred.

Responsibilities

• Provide in-depth technical expertise on cell growth and bioreactor culture for biologics drug substance production, in support of technology transfer to manufacturing and process improvement activities.
• Proactively identify opportunities to generate experimental data for improving process robustness, increased process understanding, and/or troubleshooting issues.
• Lead cross-functional project teams, collaborate with technical development, and support engineering and GMP batch production.
• Own laboratory studies including experimental design, planning, execution, and documentation.
• Support investigations as the technical SME as needed.
• Prevent process deviation recurrences through implementation of proper corrective measures.
• Represent the technical manufacturing process perspective on items such as change control, continuous improvement, capital projects, and new component introduction.
• Support Process Validation batch production activities and assure smooth transition of process to commercial operations.
• Develop technical conclusion reports summarizing process validation activities.
• Effectively and efficiently communicate analysis of manufacturing data and experimental results to key stakeholders.
• Author technical reports as needed.

Benefits

• The base compensation range for this role is: $103,000.00-$134,000.00
• Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.
• Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.
• In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being; including, but not limited to: Medical, Dental, Vision, & Life insurances
• Fitness & Wellness programs including a fitness reimbursement
• Short- and Long-Term Disability insurance
• A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
• Up to 12 company paid holidays + 3 paid days off for Personal Significance
• 80 hours of sick time per calendar year
• Paid Maternity and Parental Leave benefit
• 401(k) program participation with company matched contributions
• Employee stock purchase plan
• Tuition reimbursement of up to $10,000 per calendar year
• Employee Resource Groups participation

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees