Provide services as a Biologist (Cell Culture) in support of the overall functions of the VRC/VPP within the National Institute of Allergy and Infectious Diseases (NIAID). Develop viral vaccines, recombinant proteins and/or virus-like particles or monoclonal antibodies. Perform investigations and documentation of cell line growth, optimization of cell culture/fermentation conditions, cell culture technology development, improvement of cell culture platforms, modeling of cell culture behavior, troubleshooting of cell culture/fermentation processes, and tech transfer of defined cell culture/fermentation processes to the clinical production facility. Capture process descriptions and results in lab notebooks, tech transfer documents, and technical reports. Independently set-up and operate bioreactors and other cell culture equipment required for development studies. Perform cell culture experimental studies. Participate in project and laboratory meetings, keep current with compliance obligations, and be responsible for maintenance of the laboratory and equipment. Contribute results and studies for publication in peer reviewed journals. Develop experimental protocols (EP) for cell culture development studies for transients and/or stable cell line project and present finding, including: o Coordinate with Project leads and Project Management on EP goals o Design experimental conditions o Compile data into project-based presentations o Communicate results in project meetings Serve as SME in new technologies initiatives, such as perfusion-based cell culture methods, and novel transient transfection techniques. Contribute to Lab Operations initiatives including: o Responsible for FLEX2 bioanalyzer maintenance/troubleshooting o Responsible for upkeep of BIOS 16 Floor centrifuge maintenance and consumables supplies o Coordinate with Lab Operations manager on Lab Organizational efforts (e.g. 5S, KANBAN)
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Job Type
Full-time
Career Level
Mid Level
Number of Employees
251-500 employees