Software Development Engineer II

Fred Hutchinson Cancer Center • Seattle, WA

1d • Hybrid

About The Position

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington. With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality. At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. The Human Biology Division cultivates interdisciplinary research to advance understanding of human biology and the complex problems of neoplasia and other human diseases. The division is structured to foster laboratory-based and computational research at the interface of basic, clinical and population sciences. The Holland Lab is seeking a Software Development Engineer II to drive the Oncoscape platform, a production-grade system for cancer research. This hybrid role combines full-stack software engineering with hands-on data science, with control over both the product and the analysis of large-scale clinical and genomic datasets. This role will have the opportunity to work partially at our campus and remotely.

Requirements

• Bachelor’s degree in computer science or equivalent combination of education and experience.
• Minimum of 3-6 years of directly related experience.
• Strong analytical abilities and problem-solving skills.
• Knowledge of relational databases and T-SQL.
• Solid understanding of Object-Oriented Programming concepts, data structures and algorithms.
• Understanding of specific programming languages.
• Other department-determined skills or experience may be required.

Nice To Haves

• Strong experience designing scalable, secure backend systems and relational data models, particularly with PostgreSQL (Supabase experience is a plus).
• Familiarity with modern genomics workflows and their application to precision oncology and clinical decision-making.
• Comfortable operating in ambiguous, fast-moving environments, contributing to both technical architecture and product strategy.
• Experience working in cross-functional teams, translating complex scientific requirements into intuitive, production-grade software.
• 3+ years of experience building and shipping full-stack applications from zero to production in clinical or biomedical research environments, using React, TypeScript, and Next.js.
• 3+ years of experience in data science or computational research, working with large-scale data sets using distributed frameworks such as PySpark.
• Demonstrated expertise in high-dimensional data analysis, including dimensionality reduction techniques (e.g., UMAP, PaCMAP, t-SNE) in oncology or genomics contexts.
• Proven ability to own and architect end-to-end, data-intensive systems, making sound tradeoffs across frontend, backend, and data processing layers.

Responsibilities

• Follow software development best practices to design and develop software features to meet end user specifications.
• Test & debug new and modified software.
• Assist in the analysis of application requirements as requested.
• Assist in creation of application architecture and design for small projects.
• Provide tier 2 support of software, troubleshoot user problems.
• Create and maintain technical documentation.
• Collaborate with and provide documentation for end users.
• Participate in code and design reviews.
• May be responsible for providing on-call support.
• Other duties as assigned.

Benefits

• Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security.
• Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 501-1,000 employees